Mitchison TJ - Search Results

1

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Wang Y, Lee YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ. Wang Y, et al. Among authors: mitchison tj. Elife. 2014 May 20;3:e01763. doi: 10.7554/eLife.01763. Elife. 2014. PMID: 24844244 Free PMC article.

2

Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen.

Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N. Kwiatkowski N, et al. ACS Chem Biol. 2012 Jan 20;7(1):185-96. doi: 10.1021/cb200305u. Epub 2011 Oct 21. ACS Chem Biol. 2012. PMID: 21992004 Free PMC article.

3

Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.

Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ. Wang Y, et al. Among authors: mitchison tj. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9810-5. doi: 10.1073/pnas.1606862113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528663 Free PMC article.

4

Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Wang Y, Li YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ. Wang Y, et al. Among authors: mitchison tj. Elife. 2018 Mar 12;7:e36414. doi: 10.7554/eLife.36414. Elife. 2018. PMID: 29528283 Free PMC article. No abstract available.

5

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models.

Silva MC, Ferguson FM, Cai Q, Donovan KA, Nandi G, Patnaik D, Zhang T, Huang HT, Lucente DE, Dickerson BC, Mitchison TJ, Fischer ES, Gray NS, Haggarty SJ. Silva MC, et al. Among authors: mitchison tj. Elife. 2019 Mar 25;8:e45457. doi: 10.7554/eLife.45457. Elife. 2019. PMID: 30907729 Free PMC article.

6

Tubulin Resists Degradation by Cereblon-Recruiting PROTACs.

Gasic I, Groendyke BJ, Nowak RP, Yuan JC, Kalabathula J, Fischer ES, Gray NS, Mitchison TJ. Gasic I, et al. Among authors: mitchison tj. Cells. 2020 Apr 27;9(5):1083. doi: 10.3390/cells9051083. Cells. 2020. PMID: 32349222 Free PMC article.

7

A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes.

Dorer RK, Zhong S, Tallarico JA, Wong WH, Mitchison TJ, Murray AW. Dorer RK, et al. Among authors: mitchison tj. Curr Biol. 2005 Jun 7;15(11):1070-6. doi: 10.1016/j.cub.2005.05.020. Curr Biol. 2005. PMID: 15936280 Free article.

8

Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition.

Ozlü N, Monigatti F, Renard BY, Field CM, Steen H, Mitchison TJ, Steen JJ. Ozlü N, et al. Among authors: mitchison tj. Mol Cell Proteomics. 2010 Feb;9(2):336-50. doi: 10.1074/mcp.M900308-MCP200. Epub 2009 Sep 28. Mol Cell Proteomics. 2010. PMID: 19786723 Free PMC article.

9

Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells.

Tang Y, Orth JD, Xie T, Mitchison TJ. Tang Y, et al. Among authors: mitchison tj. Cancer Lett. 2011 Nov 1;310(1):15-24. doi: 10.1016/j.canlet.2011.05.024. Epub 2011 Jun 24. Cancer Lett. 2011. PMID: 21782324 Free PMC article.

10

Physical basis of large microtubule aster growth.

Ishihara K, Korolev KS, Mitchison TJ. Ishihara K, et al. Among authors: mitchison tj. Elife. 2016 Nov 28;5:e19145. doi: 10.7554/eLife.19145. Elife. 2016. PMID: 27892852 Free PMC article.

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