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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.
Ruf S, Hallur MS, Anchan NK, Swamy IN, Murugesan KR, Sarkar S, Narasimhulu LK, Putta VPRK, Shaik S, Chandrasekar DV, Mane VS, Kadnur SV, Suresh J, Bhamidipati RK, Singh M, Burri RR, Kristam R, Schreuder H, Czech J, Rudolph C, Marker A, Langer T, Mullangi R, Yura T, Gosu R, Kannt A, Dhakshinamoorthy S, Rajagopal S. Ruf S, et al. Among authors: langer t. Bioorg Med Chem Lett. 2018 Mar 1;28(5):922-925. doi: 10.1016/j.bmcl.2018.01.058. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29433927
Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.
Swaminathan S, Birudukota S, Thakur MK, Parveen R, Kandan S, Juluri S, Shaik S, Anand NN, Burri RR, Kristam R, Hallur MS, Rajagopal S, Schreuder H, Langer T, Rudolph C, Ruf S, Dhakshinamoorthy S, Gosu R, Kannt A. Swaminathan S, et al. Among authors: langer t. Biochem Biophys Res Commun. 2017 Sep 16;491(2):416-422. doi: 10.1016/j.bbrc.2017.07.087. Epub 2017 Jul 15. Biochem Biophys Res Commun. 2017. PMID: 28720493
A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Pilger J, Mazur A, Monecke P, Schreuder H, Elshorst B, Bartoschek S, Langer T, Schiffer A, Krimm I, Wegstroth M, Lee D, Hessler G, Wendt KU, Becker S, Griesinger C. Pilger J, et al. Among authors: langer t. Angew Chem Int Ed Engl. 2015 May 26;54(22):6511-5. doi: 10.1002/anie.201500671. Epub 2015 Apr 15. Angew Chem Int Ed Engl. 2015. PMID: 25877959
NMR characterization of kinase p38 dynamics in free and ligand-bound forms.
Vogtherr M, Saxena K, Hoelder S, Grimme S, Betz M, Schieborr U, Pescatore B, Robin M, Delarbre L, Langer T, Wendt KU, Schwalbe H. Vogtherr M, et al. Among authors: langer t. Angew Chem Int Ed Engl. 2006 Jan 30;45(6):993-7. doi: 10.1002/anie.200502770. Angew Chem Int Ed Engl. 2006. PMID: 16374788 No abstract available.
Folding and activity of cAMP-dependent protein kinase mutants.
Langer T, Sreeramulu S, Vogtherr M, Elshorst B, Betz M, Schieborr U, Saxena K, Schwalbe H. Langer T, et al. FEBS Lett. 2005 Aug 1;579(19):4049-54. doi: 10.1016/j.febslet.2005.06.015. FEBS Lett. 2005. PMID: 16026785 Free article.
922 results