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Intramuscular administration of paliperidone palmitate extended-release injectable microsuspension induces a subclinical inflammatory reaction modulating the pharmacokinetics in rats.
Darville N, van Heerden M, Vynckier A, De Meulder M, Sterkens P, Annaert P, Van den Mooter G. Darville N, et al. Among authors: van den mooter g, van heerden m. J Pharm Sci. 2014 Jul;103(7):2072-2087. doi: 10.1002/jps.24014. Epub 2014 May 20. J Pharm Sci. 2014. PMID: 24845884
Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions.
Darville N, Saarinen J, Isomäki A, Khriachtchev L, Cleeren D, Sterkens P, van Heerden M, Annaert P, Peltonen L, Santos HA, Strachan CJ, Van den Mooter G. Darville N, et al. Among authors: van den mooter g, van heerden m. Eur J Pharm Biopharm. 2015 Oct;96:338-48. doi: 10.1016/j.ejpb.2015.09.003. Epub 2015 Sep 5. Eur J Pharm Biopharm. 2015. PMID: 26347923
Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the Rat.
Darville N, van Heerden M, Erkens T, De Jonghe S, Vynckier A, De Meulder M, Vermeulen A, Sterkens P, Annaert P, Van den Mooter G. Darville N, et al. Among authors: van den mooter g, van heerden m. Toxicol Pathol. 2016 Feb;44(2):189-210. doi: 10.1177/0192623315618291. Epub 2015 Dec 23. Toxicol Pathol. 2016. PMID: 26698322
The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension.
Darville N, van Heerden M, Mariën D, De Meulder M, Rossenu S, Vermeulen A, Vynckier A, De Jonghe S, Sterkens P, Annaert P, Van den Mooter G. Darville N, et al. Among authors: van den mooter g, van heerden m. J Control Release. 2016 May 28;230:95-108. doi: 10.1016/j.jconrel.2016.03.041. Epub 2016 Apr 9. J Control Release. 2016. PMID: 27067365
Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules.
Kourula S, Derksen M, Jardi F, Jonkers S, van Heerden M, Verboven P, Theuns V, Van Asten S, Huybrechts T, Kunze A, Frazer-Mendelewska E, Lai KW, Overmeer R, Roos JL, Vries RGJ, Boj SF, Monshouwer M, Pourfarzad F, Snoeys J. Kourula S, et al. Among authors: van heerden m. Eur J Pharm Sci. 2023 Sep 1;188:106481. doi: 10.1016/j.ejps.2023.106481. Epub 2023 May 25. Eur J Pharm Sci. 2023. PMID: 37244450 Free article.
74 results