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The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.
Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA. Dopfer EP, et al. Among authors: fiala gj. Cell Rep. 2014 Jun 12;7(5):1704-1715. doi: 10.1016/j.celrep.2014.04.049. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857663 Free article.
Stoichiometry and intracellular fate of TRIM-containing TCR complexes.
Swamy M, Siegers GM, Fiala GJ, Molnar E, Dopfer EP, Fisch P, Schraven B, Schamel WW. Swamy M, et al. Among authors: fiala gj. Cell Commun Signal. 2010 Mar 18;8:5. doi: 10.1186/1478-811X-8-5. Cell Commun Signal. 2010. PMID: 20298603 Free PMC article.
Activation of the TCR complex by peptide-MHC and superantigens.
Louis-Dit-Sully C, Blumenthal B, Duchniewicz M, Beck-Garcia K, Fiala GJ, Beck-García E, Mukenhirn M, Minguet S, Schamel WW. Louis-Dit-Sully C, et al. Among authors: fiala gj. Exp Suppl. 2014;104:9-23. doi: 10.1007/978-3-0348-0726-5_2. Exp Suppl. 2014. PMID: 24214615 Review.
A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper K, Rizzi M, Speletas M, Smulski CR, Sic H, Kraus H, Salzer U, Fiala GJ, Schamel WW, Lougaris V, Plebani A, Hammarstrom L, Recher M, Germenis AE, Grimbacher B, Warnatz K, Rolink AG, Schneider P, Notarangelo LD, Eibel H. Pieper K, et al. Among authors: fiala gj. J Allergy Clin Immunol. 2014 Apr;133(4):1222-5. doi: 10.1016/j.jaci.2013.11.021. Epub 2014 Jan 7. J Allergy Clin Immunol. 2014. PMID: 24406071 No abstract available.
27 results