Helm O - Search Results

1

Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia.

Hattermann K, Sebens S, Helm O, Schmitt AD, Mentlein R, Mehdorn HM, Held-Feindt J. Hattermann K, et al. Among authors: helm o. Oncol Rep. 2014 Jul;32(1):270-6. doi: 10.3892/or.2014.3214. Epub 2014 May 23. Oncol Rep. 2014. PMID: 24859792

2

Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis.

Helm O, Held-Feindt J, Grage-Griebenow E, Reiling N, Ungefroren H, Vogel I, Krüger U, Becker T, Ebsen M, Röcken C, Kabelitz D, Schäfer H, Sebens S. Helm O, et al. Int J Cancer. 2014 Aug 15;135(4):843-61. doi: 10.1002/ijc.28736. Epub 2014 Feb 5. Int J Cancer. 2014. PMID: 24458546

3

M1 and M2: there is no "good" and "bad"-How macrophages promote malignancy-associated features in tumorigenesis.

Helm O, Held-Feindt J, Schäfer H, Sebens S. Helm O, et al. Oncoimmunology. 2014 Jul 3;3(7):e946818. doi: 10.4161/21624011.2014.946818. eCollection 2014. Oncoimmunology. 2014. PMID: 25610733 Free PMC article.

4

Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells.

Diehl K, Dinges LA, Helm O, Ammar N, Plundrich D, Arlt A, Röcken C, Sebens S, Schäfer H. Diehl K, et al. Among authors: helm o. Oncogene. 2018 Jan 4;37(1):39-51. doi: 10.1038/onc.2017.299. Epub 2017 Aug 28. Oncogene. 2018. PMID: 28846107

5

Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.

Helm O, Mennrich R, Petrick D, Goebel L, Freitag-Wolf S, Röder C, Kalthoff H, Röcken C, Sipos B, Kabelitz D, Schäfer H, Oberg HH, Wesch D, Sebens S. Helm O, et al. PLoS One. 2014 May 5;9(5):e94357. doi: 10.1371/journal.pone.0094357. eCollection 2014. PLoS One. 2014. PMID: 24797069 Free PMC article. Clinical Trial.

6

The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1.

Genrich G, Kruppa M, Lenk L, Helm O, Broich A, Freitag-Wolf S, Röcken C, Sipos B, Schäfer H, Sebens S. Genrich G, et al. Among authors: helm o. BMC Cancer. 2016 Feb 25;16:155. doi: 10.1186/s12885-016-2191-7. BMC Cancer. 2016. PMID: 26915435 Free PMC article.

7

Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1.

Radke DI, Ungefroren H, Helm O, Voigt S, Alp G, Braun H, Hübner S, Dilchert J, Sebens S, Adam D, Kalthoff H, Trauzold A. Radke DI, et al. Among authors: helm o. Cell Signal. 2016 Nov;28(11):1652-62. doi: 10.1016/j.cellsig.2016.07.016. Epub 2016 Aug 1. Cell Signal. 2016. PMID: 27492861

8

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells.

Rahn S, Zimmermann V, Viol F, Knaack H, Stemmer K, Peters L, Lenk L, Ungefroren H, Saur D, Schäfer H, Helm O, Sebens S. Rahn S, et al. Among authors: helm o. Cancer Lett. 2018 Feb 28;415:129-150. doi: 10.1016/j.canlet.2017.12.004. Epub 2017 Dec 6. Cancer Lett. 2018. PMID: 29222037

9

The antioxidant transcription factor Nrf2 modulates the stress response and phenotype of malignant as well as premalignant pancreatic ductal epithelial cells by inducing expression of the ATF3 splicing variant ΔZip2.

Kha ML, Hesse L, Deisinger F, Sipos B, Röcken C, Arlt A, Sebens S, Helm O, Schäfer H. Kha ML, et al. Among authors: helm o. Oncogene. 2019 Feb;38(9):1461-1476. doi: 10.1038/s41388-018-0518-3. Epub 2018 Oct 9. Oncogene. 2019. PMID: 30302023

10

Plant-derived saccharides and their inhibitory potential on metastasis associated cellular processes of pancreatic ductal adenocarcinoma cells.

Schöll-Naderer M, Helm O, Spencker J, Pfeifer L, Rätsch T, Sebens S, Classen B. Schöll-Naderer M, et al. Among authors: helm o. Carbohydr Res. 2020 Apr;490:107903. doi: 10.1016/j.carres.2019.107903. Epub 2019 Dec 23. Carbohydr Res. 2020. PMID: 32171073

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