Barnes JL - Search Results

1

RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species.

Manickam N, Patel M, Griendling KK, Gorin Y, Barnes JL. Manickam N, et al. Among authors: barnes jl. Am J Physiol Renal Physiol. 2014 Jul 15;307(2):F159-71. doi: 10.1152/ajprenal.00546.2013. Epub 2014 May 28. Am J Physiol Renal Physiol. 2014. PMID: 24872317 Free PMC article.

2

Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney.

Gorin Y, Block K, Hernandez J, Bhandari B, Wagner B, Barnes JL, Abboud HE. Gorin Y, et al. Among authors: barnes jl. J Biol Chem. 2005 Nov 25;280(47):39616-26. doi: 10.1074/jbc.M502412200. Epub 2005 Aug 31. J Biol Chem. 2005. PMID: 16135519 Free article.

3

NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts.

Bondi CD, Manickam N, Lee DY, Block K, Gorin Y, Abboud HE, Barnes JL. Bondi CD, et al. Among authors: barnes jl. J Am Soc Nephrol. 2010 Jan;21(1):93-102. doi: 10.1681/ASN.2009020146. Epub 2009 Nov 19. J Am Soc Nephrol. 2010. PMID: 19926889 Free PMC article.

4

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases.

Barnes JL, Gorin Y. Barnes JL, et al. Kidney Int. 2011 May;79(9):944-56. doi: 10.1038/ki.2010.516. Epub 2011 Feb 9. Kidney Int. 2011. PMID: 21307839 Free PMC article. Review.

5

ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice.

Ford BM, Eid AA, Göőz M, Barnes JL, Gorin YC, Abboud HE. Ford BM, et al. Among authors: barnes jl. Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F323-32. doi: 10.1152/ajprenal.00522.2012. Epub 2013 May 15. Am J Physiol Renal Physiol. 2013. PMID: 23678045 Free PMC article.

6

Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.

Gorin Y, Cavaglieri RC, Khazim K, Lee DY, Bruno F, Thakur S, Fanti P, Szyndralewiez C, Barnes JL, Block K, Abboud HE. Gorin Y, et al. Among authors: barnes jl. Am J Physiol Renal Physiol. 2015 Jun 1;308(11):F1276-87. doi: 10.1152/ajprenal.00396.2014. Epub 2015 Feb 4. Am J Physiol Renal Physiol. 2015. PMID: 25656366 Free PMC article.

7

Activation of AMP-activated protein kinase prevents TGF-β1-induced epithelial-mesenchymal transition and myofibroblast activation.

Thakur S, Viswanadhapalli S, Kopp JB, Shi Q, Barnes JL, Block K, Gorin Y, Abboud HE. Thakur S, et al. Among authors: barnes jl. Am J Pathol. 2015 Aug;185(8):2168-80. doi: 10.1016/j.ajpath.2015.04.014. Epub 2015 Jun 10. Am J Pathol. 2015. PMID: 26071397 Free PMC article.

8

HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice.

Nayak BK, Shanmugasundaram K, Friedrichs WE, Cavaglierii RC, Patel M, Barnes J, Block K. Nayak BK, et al. Diabetes. 2016 May;65(5):1387-97. doi: 10.2337/db15-0519. Epub 2016 Feb 23. Diabetes. 2016. PMID: 26908870 Free PMC article.

9

Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.

Eid AA, Gorin Y, Fagg BM, Maalouf R, Barnes JL, Block K, Abboud HE. Eid AA, et al. Among authors: barnes jl. Diabetes. 2009 May;58(5):1201-11. doi: 10.2337/db08-1536. Epub 2009 Feb 10. Diabetes. 2009. PMID: 19208908 Free PMC article.

10

AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.

Eid AA, Ford BM, Block K, Kasinath BS, Gorin Y, Ghosh-Choudhury G, Barnes JL, Abboud HE. Eid AA, et al. Among authors: barnes jl. J Biol Chem. 2010 Nov 26;285(48):37503-12. doi: 10.1074/jbc.M110.136796. Epub 2010 Sep 22. J Biol Chem. 2010. PMID: 20861022 Free PMC article.

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