Gitler AD - Search Results

1

A cellular system that degrades misfolded proteins and protects against neurodegeneration.

Guo L, Giasson BI, Glavis-Bloom A, Brewer MD, Shorter J, Gitler AD, Yang X. Guo L, et al. Among authors: gitler ad. Mol Cell. 2014 Jul 3;55(1):15-30. doi: 10.1016/j.molcel.2014.04.030. Epub 2014 May 29. Mol Cell. 2014. PMID: 24882209 Free PMC article.

2

Prime time for alpha-synuclein.

Gitler AD, Shorter J. Gitler AD, et al. J Neurosci. 2007 Mar 7;27(10):2433-4. doi: 10.1523/JNEUROSCI.0094-07.2007. J Neurosci. 2007. PMID: 17344380 Free PMC article. No abstract available.

3

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.

Johnson BS, Snead D, Lee JJ, McCaffery JM, Shorter J, Gitler AD. Johnson BS, et al. Among authors: gitler ad. J Biol Chem. 2009 Jul 24;284(30):20329-39. doi: 10.1074/jbc.M109.010264. Epub 2009 May 22. J Biol Chem. 2009. PMID: 19465477 Free PMC article.

4

Prion-like disorders: blurring the divide between transmissibility and infectivity.

Cushman M, Johnson BS, King OD, Gitler AD, Shorter J. Cushman M, et al. Among authors: gitler ad. J Cell Sci. 2010 Apr 15;123(Pt 8):1191-201. doi: 10.1242/jcs.051672. J Cell Sci. 2010. PMID: 20356930 Free PMC article.

5

Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS.

Sun Z, Diaz Z, Fang X, Hart MP, Chesi A, Shorter J, Gitler AD. Sun Z, et al. Among authors: gitler ad. PLoS Biol. 2011 Apr;9(4):e1000614. doi: 10.1371/journal.pbio.1000614. Epub 2011 Apr 26. PLoS Biol. 2011. PMID: 21541367 Free PMC article.

6

Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS.

Bonini NM, Gitler AD. Bonini NM, et al. Among authors: gitler ad. J Mol Neurosci. 2011 Nov;45(3):676-83. doi: 10.1007/s12031-011-9548-9. Epub 2011 Jun 10. J Mol Neurosci. 2011. PMID: 21660502 Free PMC article. Review.

7

RNA-binding proteins with prion-like domains in ALS and FTLD-U.

Gitler AD, Shorter J. Gitler AD, et al. Prion. 2011 Jul-Sep;5(3):179-87. doi: 10.4161/pri.5.3.17230. Epub 2011 Jul 1. Prion. 2011. PMID: 21847013 Free PMC article. Review.

8

A yeast functional screen predicts new candidate ALS disease genes.

Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Solski JA, Williams KL, Mojsilovic-Petrovic J, Ingre C, Boylan K, Graff-Radford NR, Dickson DW, Clay-Falcone D, Elman L, McCluskey L, Greene R, Kalb RG, Lee VM, Trojanowski JQ, Ludolph A, Robberecht W, Andersen PM, Nicholson GA, Blair IP, King OD, Bonini NM, Van Deerlin V, Rademakers R, Mourelatos Z, Gitler AD. Couthouis J, et al. Among authors: gitler ad. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):20881-90. doi: 10.1073/pnas.1109434108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065782 Free PMC article.

9

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.

King OD, Gitler AD, Shorter J. King OD, et al. Among authors: gitler ad. Brain Res. 2012 Jun 26;1462:61-80. doi: 10.1016/j.brainres.2012.01.016. Epub 2012 Jan 21. Brain Res. 2012. PMID: 22445064 Free PMC article. Review.

10

Stress granules as crucibles of ALS pathogenesis.

Li YR, King OD, Shorter J, Gitler AD. Li YR, et al. Among authors: gitler ad. J Cell Biol. 2013 Apr 29;201(3):361-72. doi: 10.1083/jcb.201302044. J Cell Biol. 2013. PMID: 23629963 Free PMC article. Review.

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