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The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity.
Plotegher N, Kumar D, Tessari I, Brucale M, Munari F, Tosatto L, Belluzzi E, Greggio E, Bisaglia M, Capaldi S, Aioanei D, Mammi S, Monaco HL, Samo B, Bubacco L. Plotegher N, et al. Among authors: mammi s. Hum Mol Genet. 2014 Nov 1;23(21):5615-29. doi: 10.1093/hmg/ddu275. Epub 2014 Jun 3. Hum Mol Genet. 2014. PMID: 24895406
Dopamine quinones interact with alpha-synuclein to form unstructured adducts.
Bisaglia M, Tosatto L, Munari F, Tessari I, de Laureto PP, Mammi S, Bubacco L. Bisaglia M, et al. Among authors: mammi s. Biochem Biophys Res Commun. 2010 Apr 2;394(2):424-8. doi: 10.1016/j.bbrc.2010.03.044. Epub 2010 Mar 10. Biochem Biophys Res Commun. 2010. PMID: 20226175
143 results