Yang T - Search Results

1

Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.

Yang T, Chun YW, Stroud DM, Mosley JD, Knollmann BC, Hong C, Roden DM. Yang T, et al. Circulation. 2014 Jul 15;130(3):224-34. doi: 10.1161/CIRCULATIONAHA.113.007765. Epub 2014 Jun 3. Circulation. 2014. PMID: 24895457 Free PMC article.

2

Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes.

Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, Hohnloser SH, Shimizu W, Schwartz PJ, Stanton M, Murray KT, Norris K, George AL Jr, Roden DM. Yang P, et al. Among authors: yang t. Circulation. 2002 Apr 23;105(16):1943-8. doi: 10.1161/01.cir.0000014448.19052.4c. Circulation. 2002. PMID: 11997281

3

Phosphorylation of the IKs channel complex inhibits drug block: novel mechanism underlying variable antiarrhythmic drug actions.

Yang T, Kanki H, Roden DM. Yang T, et al. Circulation. 2003 Jul 15;108(2):132-4. doi: 10.1161/01.CIR.0000082708.86266.B8. Epub 2003 Jun 30. Circulation. 2003. PMID: 12835205

4

Atrial fibrillation in KCNE1-null mice.

Temple J, Frias P, Rottman J, Yang T, Wu Y, Verheijck EE, Zhang W, Siprachanh C, Kanki H, Atkinson JB, King P, Anderson ME, Kupershmidt S, Roden DM. Temple J, et al. Among authors: yang t. Circ Res. 2005 Jul 8;97(1):62-9. doi: 10.1161/01.RES.0000173047.42236.88. Epub 2005 Jun 9. Circ Res. 2005. PMID: 15947250

5

Unmasking of brugada syndrome by lithium.

Darbar D, Yang T, Churchwell K, Wilde AA, Roden DM. Darbar D, et al. Among authors: yang t. Circulation. 2005 Sep 13;112(11):1527-31. doi: 10.1161/CIRCULATIONAHA.105.548487. Epub 2005 Sep 6. Circulation. 2005. PMID: 16144991 Free PMC article.

6

New mechanism contributing to drug-induced arrhythmia: rescue of a misprocessed LQT3 mutant.

Liu K, Yang T, Viswanathan PC, Roden DM. Liu K, et al. Among authors: yang t. Circulation. 2005 Nov 22;112(21):3239-46. doi: 10.1161/CIRCULATIONAHA.105.564008. Circulation. 2005. PMID: 16301357

7

Voltage-gated sodium channels are required for heart development in zebrafish.

Chopra SS, Stroud DM, Watanabe H, Bennett JS, Burns CG, Wells KS, Yang T, Zhong TP, Roden DM. Chopra SS, et al. Among authors: yang t. Circ Res. 2010 Apr 30;106(8):1342-50. doi: 10.1161/CIRCRESAHA.109.213132. Epub 2010 Mar 25. Circ Res. 2010. PMID: 20339120 Free PMC article.

8

Informatic and functional approaches to identifying a regulatory region for the cardiac sodium channel.

Atack TC, Stroud DM, Watanabe H, Yang T, Hall L, Hipkens SB, Lowe JS, Leake B, Magnuson MA, Yang P, Roden DM. Atack TC, et al. Among authors: yang t, yang p. Circ Res. 2011 Jun 24;109(1):38-46. doi: 10.1161/CIRCRESAHA.110.235630. Epub 2011 May 12. Circ Res. 2011. PMID: 21566215 Free PMC article.

9

Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.

Watanabe H, Yang T, Stroud DM, Lowe JS, Harris L, Atack TC, Wang DW, Hipkens SB, Leake B, Hall L, Kupershmidt S, Chopra N, Magnuson MA, Tanabe N, Knollmann BC, George AL Jr, Roden DM. Watanabe H, et al. Among authors: yang t. Circulation. 2011 Aug 30;124(9):1001-11. doi: 10.1161/CIRCULATIONAHA.110.987248. Epub 2011 Aug 8. Circulation. 2011. PMID: 21824921 Free PMC article.

10

Increased late sodium current contributes to long QT-related arrhythmia susceptibility in female mice.

Lowe JS, Stroud DM, Yang T, Hall L, Atack TC, Roden DM. Lowe JS, et al. Among authors: yang t. Cardiovasc Res. 2012 Aug 1;95(3):300-7. doi: 10.1093/cvr/cvs160. Epub 2012 May 4. Cardiovasc Res. 2012. PMID: 22562703 Free PMC article.

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