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Protein kinase CK2 inhibition down modulates the NF-κB and STAT3 survival pathways, enhances the cellular proteotoxic stress and synergistically boosts the cytotoxic effect of bortezomib on multiple myeloma and mantle cell lymphoma cells.
Manni S, Brancalion A, Mandato E, Tubi LQ, Colpo A, Pizzi M, Cappellesso R, Zaffino F, Di Maggio SA, Cabrelle A, Marino F, Zambello R, Trentin L, Adami F, Gurrieri C, Semenzato G, Piazza F. Manni S, et al. Among authors: mandato e. PLoS One. 2013 Sep 27;8(9):e75280. doi: 10.1371/journal.pone.0075280. eCollection 2013. PLoS One. 2013. PMID: 24086494 Free PMC article.
Protein kinase CK2 regulates AKT, NF-κB and STAT3 activation, stem cell viability and proliferation in acute myeloid leukemia.
Quotti Tubi L, Canovas Nunes S, Brancalion A, Doriguzzi Breatta E, Manni S, Mandato E, Zaffino F, Macaccaro P, Carrino M, Gianesin K, Trentin L, Binotto G, Zambello R, Semenzato G, Gurrieri C, Piazza F. Quotti Tubi L, et al. Among authors: mandato e. Leukemia. 2017 Feb;31(2):292-300. doi: 10.1038/leu.2016.209. Epub 2016 Aug 1. Leukemia. 2017. PMID: 27479180
CK2β-regulated signaling controls B cell differentiation and function.
Quotti Tubi L, Mandato E, Canovas Nunes S, Arjomand A, Zaffino F, Manni S, Casellato A, Macaccaro P, Vitulo N, Zumerle S, Filhol O, Boldyreff B, Siebel CW, Viola A, Valle G, Mainoldi F, Casola S, Cancila V, Gulino A, Tripodo C, Pizzi M, Dei Tos AP, Trentin L, Semenzato G, Piazza F. Quotti Tubi L, et al. Among authors: mandato e. Front Immunol. 2023 Jan 11;13:959138. doi: 10.3389/fimmu.2022.959138. eCollection 2022. Front Immunol. 2023. PMID: 36713383 Free PMC article.
CK2β Regulates Hematopoietic Stem Cell Biology and Erythropoiesis.
Quotti Tubi L, Canovas Nunes S, Mandato E, Pizzi M, Vitulo N, D'Agnolo M, Colombatti R, Martella M, Boaro MP, Doriguzzi Breatta E, Fregnani A, Spinello Z, Nabergoj M, Filhol O, Boldyreff B, Albiero M, Fadini GP, Gurrieri C, Vianello F, Semenzato G, Manni S, Trentin L, Piazza F. Quotti Tubi L, et al. Among authors: mandato e. Hemasphere. 2023 Nov 23;7(12):e978. doi: 10.1097/HS9.0000000000000978. eCollection 2023 Dec. Hemasphere. 2023. PMID: 38026791 Free PMC article.
21 results