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Regulation of the VHL/HIF-1 pathway by DJ-1.
Parsanejad M, Zhang Y, Qu D, Irrcher I, Rousseaux MW, Aleyasin H, Kamkar F, Callaghan S, Slack RS, Mak TW, Lee S, Figeys D, Park DS. Parsanejad M, et al. Among authors: aleyasin h. J Neurosci. 2014 Jun 4;34(23):8043-50. doi: 10.1523/JNEUROSCI.1244-13.2014. J Neurosci. 2014. PMID: 24899725 Free PMC article.
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.
Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, Kim RH, Chen CX, Fon EA, Slack RS, Harper ME, McBride HM, Mak TW, Park DS. Irrcher I, et al. Among authors: aleyasin h. Hum Mol Genet. 2010 Oct 1;19(19):3734-46. doi: 10.1093/hmg/ddq288. Epub 2010 Jul 16. Hum Mol Genet. 2010. PMID: 20639397
DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.
Parsanejad M, Bourquard N, Qu D, Zhang Y, Huang E, Rousseaux MW, Aleyasin H, Irrcher I, Callaghan S, Vaillant DC, Kim RH, Slack RS, Mak TW, Reddy ST, Figeys D, Park DS. Parsanejad M, et al. Among authors: aleyasin h. PLoS One. 2014 Sep 11;9(9):e106601. doi: 10.1371/journal.pone.0106601. eCollection 2014. PLoS One. 2014. PMID: 25210784 Free PMC article.
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.
Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, Pownall S, Wakeham A, You-Ten AJ, Kalia SK, Horne P, Westaway D, Lozano AM, Anisman H, Park DS, Mak TW. Kim RH, et al. Among authors: aleyasin h. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5215-20. doi: 10.1073/pnas.0501282102. Epub 2005 Mar 22. Proc Natl Acad Sci U S A. 2005. PMID: 15784737 Free PMC article.
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.
Qu D, Rashidian J, Mount MP, Aleyasin H, Parsanejad M, Lira A, Haque E, Zhang Y, Callaghan S, Daigle M, Rousseaux MW, Slack RS, Albert PR, Vincent I, Woulfe JM, Park DS. Qu D, et al. Among authors: aleyasin h. Neuron. 2007 Jul 5;55(1):37-52. doi: 10.1016/j.neuron.2007.05.033. Neuron. 2007. PMID: 17610816 Free article.
37 results