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Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormone.
Shinagawa Y, Inoue T, Katsushima T, Kiguchi T, Ikenogami T, Ogawa N, Fukuda K, Hirata K, Harada K, Takagi M, Nakagawa T, Kimura S, Matsuo Y, Maekawa M, Hayashi M, Soejima Y, Takahashi M, Shindo M, Hashimoto H. Shinagawa Y, et al. Among authors: takahashi m. ACS Med Chem Lett. 2010 Dec 29;2(3):238-42. doi: 10.1021/ml100268k. eCollection 2011 Mar 10. ACS Med Chem Lett. 2010. PMID: 24900301 Free PMC article.
Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCbeta-selective inhibitors.
Tanaka M, Sagawa S, Hoshi J, Shimoma F, Yasue K, Ubukata M, Ikemoto T, Hase Y, Takahashi M, Sasase T, Ueda N, Matsushita M, Inaba T. Tanaka M, et al. Among authors: takahashi m. Bioorg Med Chem. 2006 Sep 1;14(17):5781-94. doi: 10.1016/j.bmc.2006.05.033. Epub 2006 Jun 9. Bioorg Med Chem. 2006. PMID: 16762554
Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents.
Fox BM, Sugimoto K, Iio K, Yoshida A, Zhang JK, Li K, Hao X, Labelle M, Smith ML, Rubenstein SM, Ye G, McMinn D, Jackson S, Choi R, Shan B, Ma J, Miao S, Matsui T, Ogawa N, Suzuki M, Kobayashi A, Ozeki H, Okuma C, Ishii Y, Tomimoto D, Furakawa N, Tanaka M, Matsushita M, Takahashi M, Inaba T, Sagawa S, Kayser F. Fox BM, et al. Among authors: takahashi m. J Med Chem. 2014 Apr 24;57(8):3464-83. doi: 10.1021/jm500135c. Epub 2014 Apr 8. J Med Chem. 2014. PMID: 24670009
Multiple Small Foley Balloons for Large Cardiac or Vascular Lacerations.
Oda K, Takahashi M, Terao N, Akanuma R, Hasegawa T, Usuda M, Kawatsu S. Oda K, et al. Among authors: takahashi m. Ann Thorac Surg Short Rep. 2024 Jan 20;2(2):306-308. doi: 10.1016/j.atssr.2023.12.017. eCollection 2024 Jun. Ann Thorac Surg Short Rep. 2024. PMID: 39790168 Free PMC article.
Trastuzumab-Pertuzumab Plus Eribulin or Taxane as First-Line Chemotherapy for Human Epidermal Growth Factor 2-Positive Locally Advanced/Metastatic Breast Cancer: The Randomized Noninferiority Phase III EMERALD Trial.
Yamashita T, Saji S, Takano T, Naito Y, Tsuneizumi M, Yoshimura A, Takahashi M, Tsurutani J, Iwatani T, Kitada M, Tada H, Mori N, Higuchi T, Iwasa T, Araki K, Koizumi K, Hasegawa H, Uchida Y, Morita S, Masuda N. Yamashita T, et al. Among authors: takahashi m. J Clin Oncol. 2025 Jan 9:JCO2401888. doi: 10.1200/JCO-24-01888. Online ahead of print. J Clin Oncol. 2025. PMID: 39787453
Eye Adult Changes in Thought (Eye ACT) study: Settings and report on the inaugural cohort.
Ferguson AN, Takahashi M, Pope B, Schaaf B, Cooper J, Kam J, Brush M, Gibbons LE, Lee AY, Arteburn D, Larson EB, Crane PK, Lee CS; the Eye ACT study. Ferguson AN, et al. Among authors: takahashi m. Alzheimers Dement. 2025 Jan 9;20(Suppl 2):e083941. doi: 10.1002/alz.083941. eCollection 2024 Dec. Alzheimers Dement. 2025. PMID: 39784344 Free PMC article.
Advance Care Planning Initiatives in Critical Care Centers in Japan: A Case Report.
Kamimura Y, Tsubaki M, Hattori J, Oi M, Maruhashi T, Ota H, Oki M, Takanashi K, Takahashi M, Sakurai Y, Asari Y. Kamimura Y, et al. Among authors: takahashi m. Clin Case Rep. 2025 Jan 7;13(1):e9703. doi: 10.1002/ccr3.9703. eCollection 2025 Jan. Clin Case Rep. 2025. PMID: 39780906 Free PMC article.
15,210 results
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