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Page 1
Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes.
Romine JL, St Laurent DR, Leet JE, Martin SW, Serrano-Wu MH, Yang F, Gao M, O'Boyle DR 2nd, Lemm JA, Sun JH, Nower PT, Huang XS, Deshpande MS, Meanwell NA, Snyder LB. Romine JL, et al. Among authors: leet je. ACS Med Chem Lett. 2011 Jan 11;2(3):224-9. doi: 10.1021/ml1002647. eCollection 2011 Mar 10. ACS Med Chem Lett. 2011. PMID: 24900306 Free PMC article.
Discovery of potent hepatitis C virus NS5A inhibitors with dimeric structures.
Lemm JA, Leet JE, O'Boyle DR 2nd, Romine JL, Huang XS, Schroeder DR, Alberts J, Cantone JL, Sun JH, Nower PT, Martin SW, Serrano-Wu MH, Meanwell NA, Snyder LB, Gao M. Lemm JA, et al. Among authors: leet je. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802. doi: 10.1128/AAC.00146-11. Epub 2011 May 16. Antimicrob Agents Chemother. 2011. PMID: 21576451 Free PMC article.
Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement.
Li W, Zhao W, Liu X, Huang X, Lopez OD, Leet JE, Fancher RM, Nguyen V, Goodrich J, Easter J, Hong Y, Caceres-Cortes J, Chang SY, Ma L, Belema M, Hamann LG, Gao M, Zhu M, Shu YZ, Humphreys WG, Johnson BM. Li W, et al. Among authors: leet je. Drug Metab Dispos. 2016 Jun;44(6):809-20. doi: 10.1124/dmd.115.068866. Epub 2016 Mar 30. Drug Metab Dispos. 2016. PMID: 27029743
N-Demethylation of nocathiacin I via photo-oxidation.
Li W, Huang S, Liu X, Leet JE, Cantone JL, Lam KS. Li W, et al. Among authors: leet je. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4051-3. doi: 10.1016/j.bmcl.2008.05.112. Epub 2008 Jun 4. Bioorg Med Chem Lett. 2008. PMID: 18556203
35 results