Page P - Search Results

1

Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists.

Crosignani S, Jorand-Lebrun C, Page P, Campbell G, Colovray V, Missotten M, Humbert Y, Cleva C, Arrighi JF, Gaudet M, Johnson Z, Ferro P, Chollet A. Crosignani S, et al. Among authors: page p. ACS Med Chem Lett. 2011 Jun 9;2(8):644-9. doi: 10.1021/ml2001196. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900359 Free PMC article.

2

Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.

Crosignani S, Page P, Missotten M, Colovray V, Cleva C, Arrighi JF, Atherall J, Macritchie J, Martin T, Humbert Y, Gaudet M, Pupowicz D, Maio M, Pittet PA, Golzio L, Giachetti C, Rocha C, Bernardinelli G, Filinchuk Y, Scheer A, Schwarz MK, Chollet A. Crosignani S, et al. Among authors: page p. J Med Chem. 2008 Apr 10;51(7):2227-43. doi: 10.1021/jm701383e. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318469

3

Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP).

Cirillo R, Tos EG, Page P, Missotten M, Quattropani A, Scheer A, Schwarz MK, Chollet A. Cirillo R, et al. Among authors: page p. Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9. doi: 10.1016/j.ajog.2007.02.010. Am J Obstet Gynecol. 2007. PMID: 17618756 Clinical Trial.

4

First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis.

Laleu B, Gaggini F, Orchard M, Fioraso-Cartier L, Cagnon L, Houngninou-Molango S, Gradia A, Duboux G, Merlot C, Heitz F, Szyndralewiez C, Page P. Laleu B, et al. Among authors: page p. J Med Chem. 2010 Nov 11;53(21):7715-30. doi: 10.1021/jm100773e. J Med Chem. 2010. PMID: 20942471

5

Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors.

Gaggini F, Laleu B, Orchard M, Fioraso-Cartier L, Cagnon L, Houngninou-Molango S, Gradia A, Duboux G, Merlot C, Heitz F, Szyndralewiez C, Page P. Gaggini F, et al. Among authors: page p. Bioorg Med Chem. 2011 Dec 1;19(23):6989-99. doi: 10.1016/j.bmc.2011.10.016. Epub 2011 Oct 17. Bioorg Med Chem. 2011. PMID: 22041175

6

Preterm labour: an overview of current and emerging therapeutics.

Schwarz MK, Page P. Schwarz MK, et al. Among authors: page p. Curr Med Chem. 2003 Aug;10(15):1441-68. doi: 10.2174/0929867033457331. Curr Med Chem. 2003. PMID: 12871140 Review.

7

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.

Aoyama T, Paik YH, Watanabe S, Laleu B, Gaggini F, Fioraso-Cartier L, Molango S, Heitz F, Merlot C, Szyndralewiez C, Page P, Brenner DA. Aoyama T, et al. Among authors: page p. Hepatology. 2012 Dec;56(6):2316-27. doi: 10.1002/hep.25938. Hepatology. 2012. PMID: 22806357 Free PMC article.

8

Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy.

Sedeek M, Callera G, Montezano A, Gutsol A, Heitz F, Szyndralewiez C, Page P, Kennedy CR, Burns KD, Touyz RM, Hébert RL. Sedeek M, et al. Among authors: page p. Am J Physiol Renal Physiol. 2010 Dec;299(6):F1348-58. doi: 10.1152/ajprenal.00028.2010. Epub 2010 Jul 14. Am J Physiol Renal Physiol. 2010. PMID: 20630933 Free article.

9

Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.

Garrido-Urbani S, Jemelin S, Deffert C, Carnesecchi S, Basset O, Szyndralewiez C, Heitz F, Page P, Montet X, Michalik L, Arbiser J, Rüegg C, Krause KH, Imhof BA. Garrido-Urbani S, et al. Among authors: page p. PLoS One. 2011 Feb 7;6(2):e14665. doi: 10.1371/journal.pone.0014665. PLoS One. 2011. PMID: 21326871 Free PMC article.

10

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo.

Jiang JX, Chen X, Serizawa N, Szyndralewiez C, Page P, Schröder K, Brandes RP, Devaraj S, Török NJ. Jiang JX, et al. Among authors: page p. Free Radic Biol Med. 2012 Jul 15;53(2):289-96. doi: 10.1016/j.freeradbiomed.2012.05.007. Epub 2012 May 19. Free Radic Biol Med. 2012. PMID: 22618020 Free PMC article.

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