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Page 1
Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo.
Dowling JE, Alimzhanov M, Bao L, Block MH, Chuaqui C, Cooke EL, Denz CR, Hird A, Huang S, Larsen NA, Peng B, Pontz TW, Rivard-Costa C, Saeh JC, Thakur K, Ye Q, Zhang T, Lyne PD. Dowling JE, et al. Among authors: cooke el. ACS Med Chem Lett. 2013 Jul 3;4(8):800-5. doi: 10.1021/ml400197u. eCollection 2013 Aug 8. ACS Med Chem Lett. 2013. PMID: 24900749 Free PMC article.
Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization.
Dowling JE, Chuaqui C, Pontz TW, Lyne PD, Larsen NA, Block MH, Chen H, Su N, Wu A, Russell D, Pollard H, Lee JW, Peng B, Thakur K, Ye Q, Zhang T, Brassil P, Racicot V, Bao L, Denz CR, Cooke E. Dowling JE, et al. ACS Med Chem Lett. 2012 Jan 24;3(4):278-83. doi: 10.1021/ml200257n. eCollection 2012 Apr 12. ACS Med Chem Lett. 2012. PMID: 24900464 Free PMC article.
Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases.
Gingipalli L, Block MH, Bao L, Cooke E, Dakin LA, Denz CR, Ferguson AD, Johannes JW, Larsen NA, Lyne PD, Pontz TW, Wang T, Wu X, Wu A, Zhang HJ, Zheng X, Dowling JE, Lamb ML. Gingipalli L, et al. Bioorg Med Chem Lett. 2018 May 1;28(8):1336-1341. doi: 10.1016/j.bmcl.2018.03.018. Epub 2018 Mar 7. Bioorg Med Chem Lett. 2018. PMID: 29559278
Pan-European study of genotypes and phenotypes in the Arabidopsis relative Cardamine hirsuta reveals how adaptation, demography, and development shape diversity patterns.
Baumgarten L, Pieper B, Song B, Mane S, Lempe J, Lamb J, Cooke EL, Srivastava R, Strütt S, Žanko D, Casimiro PG, Hallab A, Cartolano M, Tattersall AD, Huettel B, Filatov DA, Pavlidis P, Neuffer B, Bazakos C, Schaefer H, Mott R, Gan X, Alonso-Blanco C, Laurent S, Tsiantis M. Baumgarten L, et al. Among authors: cooke el. PLoS Biol. 2023 Jul 18;21(7):e3002191. doi: 10.1371/journal.pbio.3002191. eCollection 2023 Jul. PLoS Biol. 2023. PMID: 37463141 Free PMC article.
Spatial variation of mercury bioaccumulation in bats of Canada linked to atmospheric mercury deposition.
Chételat J, Hickey MBC, Poulain AJ, Dastoor A, Ryjkov A, McAlpine D, Vanderwolf K, Jung TS, Hale L, Cooke ELL, Hobson D, Jonasson K, Kaupas L, McCarthy S, McClelland C, Morningstar D, Norquay KJO, Novy R, Player D, Redford T, Simard A, Stamler S, Webber QMR, Yumvihoze E, Zanuttig M. Chételat J, et al. Among authors: cooke ell. Sci Total Environ. 2018 Jun 1;626:668-677. doi: 10.1016/j.scitotenv.2018.01.044. Epub 2018 Feb 19. Sci Total Environ. 2018. PMID: 29396333