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Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.
Polishchuk EV, Concilli M, Iacobacci S, Chesi G, Pastore N, Piccolo P, Paladino S, Baldantoni D, van IJzendoorn SC, Chan J, Chang CJ, Amoresano A, Pane F, Pucci P, Tarallo A, Parenti G, Brunetti-Pierri N, Settembre C, Ballabio A, Polishchuk RS. Polishchuk EV, et al. Among authors: chan j. Dev Cell. 2014 Jun 23;29(6):686-700. doi: 10.1016/j.devcel.2014.04.033. Epub 2014 Jun 5. Dev Cell. 2014. PMID: 24909901 Free PMC article.
Making light of stress.
Chan J, Chang CJ. Chan J, et al. Nat Biotechnol. 2014 Apr;32(4):337-8. doi: 10.1038/nbt.2873. Nat Biotechnol. 2014. PMID: 24714482 No abstract available.
Copper is an endogenous modulator of neural circuit spontaneous activity.
Dodani SC, Firl A, Chan J, Nam CI, Aron AT, Onak CS, Ramos-Torres KM, Paek J, Webster CM, Feller MB, Chang CJ. Dodani SC, et al. Among authors: chan j. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16280-5. doi: 10.1073/pnas.1409796111. Epub 2014 Nov 5. Proc Natl Acad Sci U S A. 2014. PMID: 25378701 Free PMC article.
Copper regulates cyclic-AMP-dependent lipolysis.
Krishnamoorthy L, Cotruvo JA Jr, Chan J, Kaluarachchi H, Muchenditsi A, Pendyala VS, Jia S, Aron AT, Ackerman CM, Wal MN, Guan T, Smaga LP, Farhi SL, New EJ, Lutsenko S, Chang CJ. Krishnamoorthy L, et al. Among authors: chan j. Nat Chem Biol. 2016 Aug;12(8):586-92. doi: 10.1038/nchembio.2098. Epub 2016 Jun 6. Nat Chem Biol. 2016. PMID: 27272565 Free PMC article.
Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas.
Hong-Hermesdorf A, Miethke M, Gallaher SD, Kropat J, Dodani SC, Chan J, Barupala D, Domaille DW, Shirasaki DI, Loo JA, Weber PK, Pett-Ridge J, Stemmler TL, Chang CJ, Merchant SS. Hong-Hermesdorf A, et al. Among authors: chan j. Nat Chem Biol. 2014 Dec;10(12):1034-42. doi: 10.1038/nchembio.1662. Epub 2014 Oct 26. Nat Chem Biol. 2014. PMID: 25344811 Free PMC article.
9,978 results