Glinghammar B - Search Results

1

Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes.

Sjogren AK, Liljevald M, Glinghammar B, Sagemark J, Li XQ, Jonebring A, Cotgreave I, Brolén G, Andersson TB. Sjogren AK, et al. Among authors: glinghammar b. Arch Toxicol. 2014 Jul;88(7):1427-37. doi: 10.1007/s00204-014-1265-z. Epub 2014 Jun 10. Arch Toxicol. 2014. PMID: 24912781

2

Prediction of drug-induced liver injury in humans by using in vitro methods: the case of ximelagatran.

Kenne K, Skanberg I, Glinghammar B, Berson A, Pessayre D, Flinois JP, Beaune P, Edebert I, Pohl CD, Carlsson S, Andersson TB. Kenne K, et al. Among authors: glinghammar b. Toxicol In Vitro. 2008 Apr;22(3):730-46. doi: 10.1016/j.tiv.2007.11.014. Epub 2007 Dec 3. Toxicol In Vitro. 2008. PMID: 18191936

3

PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes.

Thulin P, Rafter I, Stockling K, Tomkiewicz C, Norjavaara E, Aggerbeck M, Hellmold H, Ehrenborg E, Andersson U, Cotgreave I, Glinghammar B. Thulin P, et al. Among authors: glinghammar b. Toxicol Appl Pharmacol. 2008 Aug 15;231(1):1-9. doi: 10.1016/j.taap.2008.03.007. Epub 2008 Mar 26. Toxicol Appl Pharmacol. 2008. PMID: 18455211

4

Isoforms of alanine aminotransferases in human tissues and serum--differential tissue expression using novel antibodies.

Lindblom P, Rafter I, Copley C, Andersson U, Hedberg JJ, Berg AL, Samuelsson A, Hellmold H, Cotgreave I, Glinghammar B. Lindblom P, et al. Among authors: glinghammar b. Arch Biochem Biophys. 2007 Oct 1;466(1):66-77. doi: 10.1016/j.abb.2007.07.023. Epub 2007 Aug 11. Arch Biochem Biophys. 2007. PMID: 17826732

5

Detection of the mitochondrial and catalytically active alanine aminotransferase in human tissues and plasma.

Glinghammar B, Rafter I, Lindström AK, Hedberg JJ, Andersson HB, Lindblom P, Berg AL, Cotgreave I. Glinghammar B, et al. Int J Mol Med. 2009 May;23(5):621-31. doi: 10.3892/ijmm_00000173. Int J Mol Med. 2009. PMID: 19360321

6

Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans.

Rafter I, Gråberg T, Kotronen A, Strömmer L, Mattson CM, Kim RW, Ehrenborg E, Andersson HB, Yki-Järvinen H, Schuppe-Koistinen I, Ekblom B, Cotgreave I, Glinghammar B. Rafter I, et al. Among authors: glinghammar b. Int J Mol Med. 2012 Nov;30(5):1241-9. doi: 10.3892/ijmm.2012.1106. Epub 2012 Aug 23. Int J Mol Med. 2012. PMID: 22922605

7

The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels.

Thulin P, Bamberg K, Buler M, Dahl B, Glinghammar B. Thulin P, et al. Among authors: glinghammar b. Int J Mol Med. 2016 Sep;38(3):961-8. doi: 10.3892/ijmm.2016.2681. Epub 2016 Jul 14. Int J Mol Med. 2016. PMID: 27430334

8

Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts.

Thulin P, Nordahl G, Gry M, Yimer G, Aklillu E, Makonnen E, Aderaye G, Lindquist L, Mattsson CM, Ekblom B, Antoine DJ, Park BK, Linder S, Harrill AH, Watkins PB, Glinghammar B, Schuppe-Koistinen I. Thulin P, et al. Among authors: glinghammar b. Liver Int. 2014 Mar;34(3):367-78. doi: 10.1111/liv.12322. Epub 2013 Oct 14. Liver Int. 2014. PMID: 24118944

9

A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat.

Thulin P, Hornby RJ, Auli M, Nordahl G, Antoine DJ, Starkey Lewis P, Goldring CE, Park BK, Prats N, Glinghammar B, Schuppe-Koistinen I. Thulin P, et al. Among authors: glinghammar b. Biomarkers. 2017 Jul;22(5):461-469. doi: 10.1080/1354750X.2016.1269131. Epub 2016 Dec 15. Biomarkers. 2017. PMID: 27978773

10

A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran.

Andersson U, Lindberg J, Wang S, Balasubramanian R, Marcusson-Ståhl M, Hannula M, Zeng C, Juhasz PJ, Kolmert J, Bäckström J, Nord L, Nilsson K, Martin S, Glinghammar B, Cederbrant K, Schuppe-Koistinen I. Andersson U, et al. Among authors: glinghammar b. Biomarkers. 2009 Dec;14(8):572-86. doi: 10.3109/13547500903261354. Biomarkers. 2009. PMID: 19780643

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