Li XQ - Search Results

1

Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes.

Sjogren AK, Liljevald M, Glinghammar B, Sagemark J, Li XQ, Jonebring A, Cotgreave I, Brolén G, Andersson TB. Sjogren AK, et al. Among authors: li xq. Arch Toxicol. 2014 Jul;88(7):1427-37. doi: 10.1007/s00204-014-1265-z. Epub 2014 Jun 10. Arch Toxicol. 2014. PMID: 24912781

2

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate.

Li XQ, Björkman A, Andersson TB, Ridderström M, Masimirembwa CM. Li XQ, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):399-407. doi: 10.1124/jpet.300.2.399. J Pharmacol Exp Ther. 2002. PMID: 11805197

3

Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data.

Li XQ, Björkman A, Andersson TB, Gustafsson LL, Masimirembwa CM. Li XQ, et al. Eur J Clin Pharmacol. 2003 Sep;59(5-6):429-42. doi: 10.1007/s00228-003-0636-9. Epub 2003 Aug 12. Eur J Clin Pharmacol. 2003. PMID: 12920490

4

Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities.

Li XQ, Andersson TB, Ahlström M, Weidolf L. Li XQ, et al. Drug Metab Dispos. 2004 Aug;32(8):821-7. doi: 10.1124/dmd.32.8.821. Drug Metab Dispos. 2004. PMID: 15258107

5

Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime.

Andersson S, Hofmann Y, Nordling A, Li XQ, Nivelius S, Andersson TB, Ingelman-Sundberg M, Johansson I. Andersson S, et al. Among authors: li xq. Drug Metab Dispos. 2005 Apr;33(4):570-8. doi: 10.1124/dmd.104.002972. Epub 2005 Jan 7. Drug Metab Dispos. 2005. PMID: 15640373

6

Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4.

Li XQ, Weidolf L, Simonsson R, Andersson TB. Li XQ, et al. J Pharmacol Exp Ther. 2005 Nov;315(2):777-87. doi: 10.1124/jpet.105.090928. Epub 2005 Aug 10. J Pharmacol Exp Ther. 2005. PMID: 16093273

7

CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.

Hayes MA, Li XQ, Grönberg G, Diczfalusy U, Andersson TB. Hayes MA, et al. Among authors: li xq. Drug Metab Dispos. 2016 Sep;44(9):1480-9. doi: 10.1124/dmd.116.070805. Epub 2016 Jul 11. Drug Metab Dispos. 2016. PMID: 27402728

8

Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers.

Li XQ, Thelingwani RS, Bertilsson L, Diczfalusy U, Andersson TB, Masimirembwa C. Li XQ, et al. J Pers Med. 2021 May 24;11(6):457. doi: 10.3390/jpm11060457. J Pers Med. 2021. PMID: 34073662 Free PMC article.

9

Oxetane Substrates of Human Microsomal Epoxide Hydrolase.

Toselli F, Fredenwall M, Svensson P, Li XQ, Johansson A, Weidolf L, Hayes MA. Toselli F, et al. Among authors: li xq. Drug Metab Dispos. 2017 Aug;45(8):966-973. doi: 10.1124/dmd.117.076489. Epub 2017 Jun 9. Drug Metab Dispos. 2017. PMID: 28600384

10

Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane.

Li XQ, Hayes MA, Grönberg G, Berggren K, Castagnoli N Jr, Weidolf L. Li XQ, et al. Drug Metab Dispos. 2016 Aug;44(8):1341-8. doi: 10.1124/dmd.116.071142. Epub 2016 Jun 2. Drug Metab Dispos. 2016. PMID: 27256986

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