Kelley SO - Search Results

1

Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion.

Jean SR, Pereira MP, Kelley SO. Jean SR, et al. Among authors: kelley so. Mol Pharm. 2014 Aug 4;11(8):2675-82. doi: 10.1021/mp500104j. Epub 2014 Jun 24. Mol Pharm. 2014. PMID: 24922525

2

Recent advances in the use of cell-penetrating peptides for medical and biological applications.

Fonseca SB, Pereira MP, Kelley SO. Fonseca SB, et al. Among authors: kelley so. Adv Drug Deliv Rev. 2009 Sep 30;61(11):953-64. doi: 10.1016/j.addr.2009.06.001. Epub 2009 Jun 16. Adv Drug Deliv Rev. 2009. PMID: 19538995 Review.

3

Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer.

Ito E, Yip KW, Katz D, Fonseca SB, Hedley DW, Chow S, Xu GW, Wood TE, Bastianutto C, Schimmer AD, Kelley SO, Liu FF. Ito E, et al. Among authors: kelley so. Mol Pharmacol. 2009 Nov;76(5):969-83. doi: 10.1124/mol.109.055277. Epub 2009 Aug 4. Mol Pharmacol. 2009. PMID: 19654225

4

Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells.

Pereira MP, Kelley SO. Pereira MP, et al. Among authors: kelley so. J Am Chem Soc. 2011 Mar 16;133(10):3260-3. doi: 10.1021/ja110246u. Epub 2011 Feb 15. J Am Chem Soc. 2011. PMID: 21322645

5

Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells.

Fonseca SB, Pereira MP, Mourtada R, Gronda M, Horton KL, Hurren R, Minden MD, Schimmer AD, Kelley SO. Fonseca SB, et al. Among authors: kelley so. Chem Biol. 2011 Apr 22;18(4):445-53. doi: 10.1016/j.chembiol.2011.02.010. Chem Biol. 2011. PMID: 21513881

6

Tuning the activity of mitochondria-penetrating peptides for delivery or disruption.

Horton KL, Pereira MP, Stewart KM, Fonseca SB, Kelley SO. Horton KL, et al. Among authors: kelley so. Chembiochem. 2012 Feb 13;13(3):476-85. doi: 10.1002/cbic.201100415. Epub 2012 Jan 11. Chembiochem. 2012. PMID: 22238158

7

Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism.

Mourtada R, Fonseca SB, Wisnovsky SP, Pereira MP, Wang X, Hurren R, Parfitt J, Larsen L, Smith RA, Murphy MP, Schimmer AD, Kelley SO. Mourtada R, et al. Among authors: kelley so. PLoS One. 2013 Apr 9;8(4):e60253. doi: 10.1371/journal.pone.0060253. Print 2013. PLoS One. 2013. PMID: 23585833 Free PMC article.

8

Targeted delivery of doxorubicin to mitochondria.

Chamberlain GR, Tulumello DV, Kelley SO. Chamberlain GR, et al. Among authors: kelley so. ACS Chem Biol. 2013 Jul 19;8(7):1389-95. doi: 10.1021/cb400095v. Epub 2013 Apr 23. ACS Chem Biol. 2013. PMID: 23590228

9

Tuning the intracellular bacterial targeting of peptidic vectors.

Lei EK, Pereira MP, Kelley SO. Lei EK, et al. Among authors: kelley so. Angew Chem Int Ed Engl. 2013 Sep 9;52(37):9660-3. doi: 10.1002/anie.201302265. Epub 2013 Jul 26. Angew Chem Int Ed Engl. 2013. PMID: 23893882 No abstract available.

10

Targeting mitochondrial DNA with a platinum-based anticancer agent.

Wisnovsky SP, Wilson JJ, Radford RJ, Pereira MP, Chan MR, Laposa RR, Lippard SJ, Kelley SO. Wisnovsky SP, et al. Among authors: kelley so. Chem Biol. 2013 Nov 21;20(11):1323-8. doi: 10.1016/j.chembiol.2013.08.010. Epub 2013 Oct 31. Chem Biol. 2013. PMID: 24183971 Free PMC article.

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