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Page 1
Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits.
Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-Lozano R, Macín-Pérez G, Granados-Arriola J, Huntsman S, Galanter JM, Via M, Ford JG, Chapela R, Rodriguez-Cintron W, Rodríguez-Santana JR, Romieu I, Sienra-Monge JJ, del Rio Navarro B, London SJ, Ruiz-Linares A, Garcia-Herrera R, Estrada K, Hidalgo-Miranda A, Jimenez-Sanchez G, Carnevale A, Soberón X, Canizales-Quinteros S, Rangel-Villalobos H, Silva-Zolezzi I, Burchard EG, Bustamante CD. Moreno-Estrada A, et al. Science. 2014 Jun 13;344(6189):1280-5. doi: 10.1126/science.1251688. Epub 2014 Jun 12. Science. 2014. PMID: 24926019 Free PMC article.
The ATP-binding cassette transporter A1 R230C variant affects HDL cholesterol levels and BMI in the Mexican population: association with obesity and obesity-related comorbidities.
Villarreal-Molina MT, Aguilar-Salinas CA, Rodríguez-Cruz M, Riaño D, Villalobos-Comparan M, Coral-Vazquez R, Menjivar M, Yescas-Gomez P, Königsoerg-Fainstein M, Romero-Hidalgo S, Tusie-Luna MT, Canizales-Quinteros S; Metabolic Study Group. Villarreal-Molina MT, et al. Diabetes. 2007 Jul;56(7):1881-7. doi: 10.2337/db06-0905. Epub 2007 Feb 7. Diabetes. 2007. PMID: 17287470
Association of the ATP-binding cassette transporter A1 R230C variant with early-onset type 2 diabetes in a Mexican population.
Villarreal-Molina MT, Flores-Dorantes MT, Arellano-Campos O, Villalobos-Comparan M, Rodríguez-Cruz M, Miliar-García A, Huertas-Vazquez A, Menjivar M, Romero-Hidalgo S, Wacher NH, Tusie-Luna MT, Cruz M, Aguilar-Salinas CA, Canizales-Quinteros S; Metabolic Study Group. Villarreal-Molina MT, et al. Diabetes. 2008 Feb;57(2):509-13. doi: 10.2337/db07-0484. Epub 2007 Nov 14. Diabetes. 2008. PMID: 18003760
The FTO gene is associated with adulthood obesity in the Mexican population.
Villalobos-Comparán M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodríguez-Cruz M, García-Ulloa AC, Robles L, Huertas-Vázquez A, Saucedo-Villarreal N, López-Alarcón M, Sánchez-Muñoz F, Domínguez-López A, Gutiérrez-Aguilar R, Menjivar M, Coral-Vázquez R, Hernández-Stengele G, Vital-Reyes VS, Acuña-Alonzo V, Romero-Hidalgo S, Ruiz-Gómez DG, Riaño-Barros D, Herrera MF, Gómez-Pérez FJ, Froguel P, García-García E, Teresa Tusié-Luna M, Aguilar-Salinas CA, Canizales-Quinteros S. Villalobos-Comparán M, et al. Obesity (Silver Spring). 2008 Oct;16(10):2296-301. doi: 10.1038/oby.2008.367. Epub 2008 Jul 31. Obesity (Silver Spring). 2008. PMID: 18719664 Free article.
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.
Acuña-Alonzo V, Flores-Dorantes T, Kruit JK, Villarreal-Molina T, Arellano-Campos O, Hünemeier T, Moreno-Estrada A, Ortiz-López MG, Villamil-Ramírez H, León-Mimila P, Villalobos-Comparan M, Jacobo-Albavera L, Ramírez-Jiménez S, Sikora M, Zhang LH, Pape TD, Granados-Silvestre Mde A, Montufar-Robles I, Tito-Alvarez AM, Zurita-Salinas C, Bustos-Arriaga J, Cedillo-Barrón L, Gómez-Trejo C, Barquera-Lozano R, Vieira-Filho JP, Granados J, Romero-Hidalgo S, Huertas-Vázquez A, González-Martín A, Gorostiza A, Bonatto SL, Rodríguez-Cruz M, Wang L, Tusié-Luna T, Aguilar-Salinas CA, Lisker R, Moises RS, Menjivar M, Salzano FM, Knowler WC, Bortolini MC, Hayden MR, Baier LJ, Canizales-Quinteros S. Acuña-Alonzo V, et al. Hum Mol Genet. 2010 Jul 15;19(14):2877-85. doi: 10.1093/hmg/ddq173. Epub 2010 Apr 23. Hum Mol Genet. 2010. PMID: 20418488 Free PMC article.
Association of R230C ABCA1 gene variant with low HDL-C levels and abnormal HDL subclass distribution in Mexican school-aged children.
Flores-Dorantes T, Arellano-Campos O, Posadas-Sánchez R, Villarreal-Molina T, Medina-Urrutia A, Romero-Hidalgo S, Yescas-Gómez P, Pérez-Méndez O, Jorge-Galarza E, Tusié-Luna T, Villalobos-Comparán M, Jacobo-Albavera L, Villamil-Ramírez H, López-Contreras BE, Aguilar-Salinas CA, Posadas-Romero C, Canizales-Quinteros S. Flores-Dorantes T, et al. Clin Chim Acta. 2010 Sep 6;411(17-18):1214-7. doi: 10.1016/j.cca.2010.04.025. Epub 2010 Apr 26. Clin Chim Acta. 2010. PMID: 20427018
Carbohydrate intake modulates the effect of the ABCA1-R230C variant on HDL cholesterol concentrations in premenopausal women.
Romero-Hidalgo S, Villarreal-Molina T, González-Barrios JA, Canizales-Quinteros S, Rodríguez-Arellano ME, Yañez-Velazco LB, Bernal-Alcantara DA, Villa AR, Antuna-Puente B, Acuña-Alonzo V, Merino-García JL, Moreno-Sandoval HN, Carnevale A. Romero-Hidalgo S, et al. J Nutr. 2012 Feb;142(2):278-83. doi: 10.3945/jn.111.152421. Epub 2011 Dec 21. J Nutr. 2012. PMID: 22190032 Free article.
PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.
Villalobos-Comparán M, Villamil-Ramírez H, Villarreal-Molina T, Larrieta-Carrasco E, León-Mimila P, Romero-Hidalgo S, Jacobo-Albavera L, Liceaga-Fuentes AE, Campos-Pérez FJ, López-Contreras BE, Tusié-Luna T, Del Río-Navarro BE, Aguilar-Salinas CA, Canizales-Quinteros S. Villalobos-Comparán M, et al. PLoS One. 2012;7(6):e39037. doi: 10.1371/journal.pone.0039037. Epub 2012 Jun 21. PLoS One. 2012. PMID: 22737226 Free PMC article.
43 results