Preece A - Search Results

1

Effects of moderate hepatic impairment on the pharmacokinetic properties and tolerability of umeclidinium and vilanterol in inhalational umeclidinium monotherapy and umeclidinium/vilanterol combination therapy: an open-label, nonrandomized study.

Mehta R, Hardes K, Kelleher D, Preece A, Tombs L, Brealey N. Mehta R, et al. Among authors: preece a. Clin Ther. 2014 Jul 1;36(7):1016-1027.e2. doi: 10.1016/j.clinthera.2014.05.002. Epub 2014 Jun 17. Clin Ther. 2014. PMID: 24947493 Clinical Trial.

2

Safety, tolerability, pharmacodynamics and pharmacokinetics of umeclidinium and vilanterol alone and in combination: a randomized crossover trial.

Kelleher DL, Mehta RS, Jean-Francois BM, Preece AF, Blowers J, Crater GD, Thomas P. Kelleher DL, et al. PLoS One. 2012;7(12):e50716. doi: 10.1371/journal.pone.0050716. Epub 2012 Dec 17. PLoS One. 2012. PMID: 23284643 Free PMC article. Clinical Trial.

3

Effect of verapamil on systemic exposure and safety of umeclidinium and vilanterol: a randomized and open-label study.

Mehta R, Kelleher D, Preece A, Hughes S, Crater G. Mehta R, et al. Among authors: preece a. Int J Chron Obstruct Pulmon Dis. 2013;8:159-67. doi: 10.2147/COPD.S40859. Epub 2013 Mar 27. Int J Chron Obstruct Pulmon Dis. 2013. PMID: 23569370 Free PMC article. Clinical Trial.

4

A randomized, placebo- and moxifloxacin-controlled thorough QT study of umeclidinium monotherapy and umeclidinium/vilanterol combination in healthy subjects.

Kelleher D, Tombs L, Preece A, Brealey N, Mehta R. Kelleher D, et al. Among authors: preece a. Pulm Pharmacol Ther. 2014 Oct;29(1):49-57. doi: 10.1016/j.pupt.2014.07.002. Epub 2014 Jul 12. Pulm Pharmacol Ther. 2014. PMID: 25020273 Clinical Trial.

5

Effect of severe renal impairment on umeclidinium and umeclidinium/vilanterol pharmacokinetics and safety: a single-blind, nonrandomized study.

Mehta R, Hardes K, Brealey N, Tombs L, Preece A, Kelleher D. Mehta R, et al. Among authors: preece a. Int J Chron Obstruct Pulmon Dis. 2014 Dec 18;10:15-23. doi: 10.2147/COPD.S68094. eCollection 2015. Int J Chron Obstruct Pulmon Dis. 2014. PMID: 25565796 Free PMC article. Clinical Trial.

6

Initial assessment of single and repeat doses of inhaled umeclidinium in patients with chronic obstructive pulmonary disease: two randomised studies.

Tal-Singer R, Cahn A, Mehta R, Preece A, Crater G, Kelleher D, Pouliquen IJ. Tal-Singer R, et al. Among authors: preece a. Eur J Pharmacol. 2013 Feb 15;701(1-3):40-8. doi: 10.1016/j.ejphar.2012.12.019. Epub 2012 Dec 28. Eur J Pharmacol. 2013. PMID: 23276660 Clinical Trial.

7

Safety, tolerability, pharmacokinetics and pharmacodynamics of single and repeat inhaled doses of umeclidinium in healthy subjects: two randomized studies.

Cahn A, Tal-Singer R, Pouliquen IJ, Mehta R, Preece A, Hardes K, Crater G, Deans A. Cahn A, et al. Among authors: preece a. Clin Drug Investig. 2013 Jul;33(7):477-88. doi: 10.1007/s40261-013-0088-7. Clin Drug Investig. 2013. PMID: 23784369 Clinical Trial.

8

Safety, tolerability and pharmacokinetics and pharmacodynamics of inhaled once-daily umeclidinium in healthy adults deficient in CYP2D6 activity: a double-blind, randomized clinical trial.

Cahn A, Mehta R, Preece A, Blowers J, Donald A. Cahn A, et al. Among authors: preece a. Clin Drug Investig. 2013 Sep;33(9):653-64. doi: 10.1007/s40261-013-0109-6. Clin Drug Investig. 2013. PMID: 23881566 Clinical Trial.

9

Effect of Disease Severity in Asthma and Chronic Obstructive Pulmonary Disease on Inhaler-Specific Inhalation Profiles Through the ELLIPTA® Dry Powder Inhaler.

Prime D, de Backer W, Hamilton M, Cahn A, Preece A, Kelleher D, Baines A, Moore A, Brealey N, Moynihan J. Prime D, et al. Among authors: preece a. J Aerosol Med Pulm Drug Deliv. 2015 Dec;28(6):486-97. doi: 10.1089/jamp.2015.1224. Epub 2015 Sep 15. J Aerosol Med Pulm Drug Deliv. 2015. PMID: 26372467 Free PMC article. Clinical Trial.

10

ELLIPTA Dry Powder Versus Metered-Dose Inhalers in an Optimized Clinical Trial Setting.

Kerwin EM, Preece A, Brintziki D, Collison KA, Sharma R. Kerwin EM, et al. Among authors: preece a. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):1843-1849. doi: 10.1016/j.jaip.2019.02.023. Epub 2019 Mar 2. J Allergy Clin Immunol Pract. 2019. PMID: 30836228 Free article. Clinical Trial.

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