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Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I.
Wang RY, Aminian A, McEntee MF, Kan SH, Simonaro CM, Lamanna WC, Lawrence R, Ellinwood NM, Guerra C, Le SQ, Dickson PI, Esko JD. Wang RY, et al. Among authors: simonaro cm. Mol Genet Metab. 2014 Aug;112(4):286-93. doi: 10.1016/j.ymgme.2014.05.015. Epub 2014 Jun 6. Mol Genet Metab. 2014. PMID: 24951454 Free PMC article.
Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses.
Schuchman EH, Ge Y, Lai A, Borisov Y, Faillace M, Eliyahu E, He X, Iatridis J, Vlassara H, Striker G, Simonaro CM. Schuchman EH, et al. Among authors: simonaro cm. PLoS One. 2013;8(1):e54459. doi: 10.1371/journal.pone.0054459. Epub 2013 Jan 24. PLoS One. 2013. PMID: 23365668 Free PMC article.
Acid ceramidase maintains the chondrogenic phenotype of expanded primary chondrocytes and improves the chondrogenic differentiation of bone marrow-derived mesenchymal stem cells.
Simonaro CM, Sachot S, Ge Y, He X, Deangelis VA, Eliyahu E, Leong DJ, Sun HB, Mason JB, Haskins ME, Richardson DW, Schuchman EH. Simonaro CM, et al. PLoS One. 2013 Apr 26;8(4):e62715. doi: 10.1371/journal.pone.0062715. Print 2013. PLoS One. 2013. PMID: 23638138 Free PMC article.
39 results