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β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.
García-Prieto J, García-Ruiz JM, Sanz-Rosa D, Pun A, García-Alvarez A, Davidson SM, Fernández-Friera L, Nuno-Ayala M, Fernández-Jiménez R, Bernal JA, Izquierdo-Garcia JL, Jimenez-Borreguero J, Pizarro G, Ruiz-Cabello J, Macaya C, Fuster V, Yellon DM, Ibanez B. García-Prieto J, et al. Among authors: bernal ja. Basic Res Cardiol. 2014 Jul;109(4):422. doi: 10.1007/s00395-014-0422-0. Epub 2014 Jun 21. Basic Res Cardiol. 2014. PMID: 24951958
Exercise triggers ARVC phenotype in mice expressing a disease-causing mutated version of human plakophilin-2.
Cruz FM, Sanz-Rosa D, Roche-Molina M, García-Prieto J, García-Ruiz JM, Pizarro G, Jiménez-Borreguero LJ, Torres M, Bernad A, Ruíz-Cabello J, Fuster V, Ibáñez B, Bernal JA. Cruz FM, et al. Among authors: bernal ja. J Am Coll Cardiol. 2015 Apr 14;65(14):1438-50. doi: 10.1016/j.jacc.2015.01.045. J Am Coll Cardiol. 2015. PMID: 25857910 Free article.
Bloodless reperfusion with the oxygen carrier HBOC-201 in acute myocardial infarction: a novel platform for cardioprotective probes delivery.
García-Ruiz JM, Galán-Arriola C, Fernández-Jiménez R, Aguero J, Sánchez-González J, García-Alvarez A, Nuno-Ayala M, Dubé GP, Zafirelis Z, López-Martín GJ, Bernal JA, Lara-Pezzi E, Fuster V, Ibáñez B. García-Ruiz JM, et al. Among authors: bernal ja. Basic Res Cardiol. 2017 Mar;112(2):17. doi: 10.1007/s00395-017-0605-6. Epub 2017 Feb 10. Basic Res Cardiol. 2017. PMID: 28188434
The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis.
Roche-Molina M, Hardwick B, Sanchez-Ramos C, Sanz-Rosa D, Gewert D, Cruz FM, Gonzalez-Guerra A, Andres V, Palma JA, Ibanez B, Mckenzie G, Bernal JA. Roche-Molina M, et al. Among authors: bernal ja. Sci Rep. 2020 Jul 15;10(1):11636. doi: 10.1038/s41598-020-68350-2. Sci Rep. 2020. PMID: 32669659 Free PMC article.
Sustained Elevated Blood Pressure Accelerates Atherosclerosis Development in a Preclinical Model of Disease.
Gonzalez-Guerra A, Roche-Molina M, García-Quintáns N, Sánchez-Ramos C, Martín-Pérez D, Lytvyn M, de Nicolás-Hernández J, Rivera-Torres J, Arroyo DF, Sanz-Rosa D, Bernal JA. Gonzalez-Guerra A, et al. Among authors: bernal ja. Int J Mol Sci. 2021 Aug 6;22(16):8448. doi: 10.3390/ijms22168448. Int J Mol Sci. 2021. PMID: 34445154 Free PMC article.
p38γ is essential for cell cycle progression and liver tumorigenesis.
Tomás-Loba A, Manieri E, González-Terán B, Mora A, Leiva-Vega L, Santamans AM, Romero-Becerra R, Rodríguez E, Pintor-Chocano A, Feixas F, López JA, Caballero B, Trakala M, Blanco Ó, Torres JL, Hernández-Cosido L, Montalvo-Romeral V, Matesanz N, Roche-Molina M, Bernal JA, Mischo H, León M, Caballero A, Miranda-Saavedra D, Ruiz-Cabello J, Nevzorova YA, Cubero FJ, Bravo J, Vázquez J, Malumbres M, Marcos M, Osuna S, Sabio G. Tomás-Loba A, et al. Among authors: bernal ja. Nature. 2019 Apr;568(7753):557-560. doi: 10.1038/s41586-019-1112-8. Epub 2019 Apr 10. Nature. 2019. PMID: 30971822
NF-kB signaling in cardiomyocytes is inhibited by sevoflurane and promoted by propofol.
Oda-Kawashima K, Sedukhina AS, Okamoto N, Lytvyn M, Minagawa K, Iwata T, Kumai T, Sato E, Inada E, Yamaura A, Sakamoto M, Roche-Molina M, Bernal JA, Sato K. Oda-Kawashima K, et al. Among authors: bernal ja. FEBS Open Bio. 2020 Feb;10(2):259-267. doi: 10.1002/2211-5463.12783. Epub 2020 Jan 15. FEBS Open Bio. 2020. PMID: 31898867 Free PMC article.
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Nicolás-Ávila JA, Lechuga-Vieco AV, Esteban-Martínez L, Sánchez-Díaz M, Díaz-García E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martínez-de-Mena R, Castejón-Vega B, Pun-García A, Través PG, Bonzón-Kulichenko E, García-Marqués F, Cussó L, A-González N, González-Guerra A, Roche-Molina M, Martin-Salamanca S, Crainiciuc G, Guzmán G, Larrazabal J, Herrero-Galán E, Alegre-Cebollada J, Lemke G, Rothlin CV, Jimenez-Borreguero LJ, Reyes G, Castrillo A, Desco M, Muñoz-Cánoves P, Ibáñez B, Torres M, Ng LG, Priori SG, Bueno H, Vázquez J, Cordero MD, Bernal JA, Enríquez JA, Hidalgo A. Nicolás-Ávila JA, et al. Among authors: bernal ja. Cell. 2020 Oct 1;183(1):94-109.e23. doi: 10.1016/j.cell.2020.08.031. Epub 2020 Sep 15. Cell. 2020. PMID: 32937105 Free article.
MYH10 activation rescues contractile defects in arrhythmogenic cardiomyopathy (ACM).
García-Quintáns N, Sacristán S, Márquez-López C, Sánchez-Ramos C, Martinez-de-Benito F, Siniscalco D, González-Guerra A, Camafeita E, Roche-Molina M, Lytvyn M, Morera D, Guillen MI, Sanguino MA, Sanz-Rosa D, Martín-Pérez D, Garcia R, Bernal JA. García-Quintáns N, et al. Among authors: bernal ja. Nat Commun. 2023 Oct 13;14(1):6461. doi: 10.1038/s41467-023-41981-5. Nat Commun. 2023. PMID: 37833253 Free PMC article.
85 results