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The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.
Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W. Shimizu K, et al. Among authors: north bj. Sci Signal. 2017 Jan 3;10(460):eaah4117. doi: 10.1126/scisignal.aah4117. Sci Signal. 2017. PMID: 28049764 Free PMC article.
Functional analysis of Cullin 3 E3 ligases in tumorigenesis.
Cheng J, Guo J, Wang Z, North BJ, Tao K, Dai X, Wei W. Cheng J, et al. Among authors: north bj. Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):11-28. doi: 10.1016/j.bbcan.2017.11.001. Epub 2017 Nov 8. Biochim Biophys Acta Rev Cancer. 2018. PMID: 29128526 Free PMC article. Review.
56 results