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Synthesis and antibacterial evaluation of new, unsymmetrical triaryl bisamidine compounds.
Nguyen ST, Williams JD, Butler MM, Ding X, Mills DM, Tashjian TF, Panchal RG, Weir SK, Moon C, Kim HO, Marsden JA, Peet NP, Bowlin TL. Nguyen ST, et al. Among authors: tashjian tf. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3366-72. doi: 10.1016/j.bmcl.2014.05.094. Epub 2014 Jun 12. Bioorg Med Chem Lett. 2014. PMID: 24969013 Free PMC article.
Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: synthesis and SAR of novel analogs of MBX 1066 and MBX 1090.
Williams JD, Nguyen ST, Gu S, Ding X, Butler MM, Tashjian TF, Opperman TJ, Panchal RG, Bavari S, Peet NP, Moir DT, Bowlin TL. Williams JD, et al. Among authors: tashjian tf. Bioorg Med Chem. 2013 Dec 15;21(24):7790-806. doi: 10.1016/j.bmc.2013.10.014. Epub 2013 Oct 25. Bioorg Med Chem. 2013. PMID: 24239389 Free PMC article.
Mutations in the Pseudomonas aeruginosa needle protein gene pscF confer resistance to phenoxyacetamide inhibitors of the type III secretion system.
Bowlin NO, Williams JD, Knoten CA, Torhan MC, Tashjian TF, Li B, Aiello D, Mecsas J, Hauser AR, Peet NP, Bowlin TL, Moir DT. Bowlin NO, et al. Among authors: tashjian tf. Antimicrob Agents Chemother. 2014;58(4):2211-20. doi: 10.1128/AAC.02795-13. Epub 2014 Jan 27. Antimicrob Agents Chemother. 2014. PMID: 24468789 Free PMC article.
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