Nicholls AW - Search Results

1

Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.

Napolitano A, Miller S, Nicholls AW, Baker D, Van Horn S, Thomas E, Rajpal D, Spivak A, Brown JR, Nunez DJ. Napolitano A, et al. Among authors: nicholls aw. PLoS One. 2014 Jul 2;9(7):e100778. doi: 10.1371/journal.pone.0100778. eCollection 2014. PLoS One. 2014. PMID: 24988476 Free PMC article. Clinical Trial.

2

Alterations in endo-lysosomal function induce similar hepatic lipid profiles in rodent models of drug-induced phospholipidosis and Sandhoff disease.

Lecommandeur E, Baker D, Cox TM, Nicholls AW, Griffin JL. Lecommandeur E, et al. Among authors: nicholls aw. J Lipid Res. 2017 Jul;58(7):1306-1314. doi: 10.1194/jlr.M073395. Epub 2017 Apr 4. J Lipid Res. 2017. PMID: 28377426 Free PMC article.

3

Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders.

Griffin JL, Nicholls AW. Griffin JL, et al. Among authors: nicholls aw. Pharmacogenomics. 2006 Oct;7(7):1095-107. doi: 10.2217/14622416.7.7.1095. Pharmacogenomics. 2006. PMID: 17054419 Review.

4

PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling.

Ament Z, West JA, Stanley E, Ashmore T, Roberts LD, Wright J, Nicholls AW, Griffin JL. Ament Z, et al. Among authors: nicholls aw. Free Radic Biol Med. 2016 Jun;95:357-68. doi: 10.1016/j.freeradbiomed.2015.11.033. Epub 2015 Nov 30. Free Radic Biol Med. 2016. PMID: 26654758 Free PMC article.

5

Decrease in Myelin-Associated Lipids Precedes Neuronal Loss and Glial Activation in the CNS of the Sandhoff Mouse as Determined by Metabolomics.

Lecommandeur E, Cachón-González MB, Boddie S, McNally BD, Nicholls AW, Cox TM, Griffin JL. Lecommandeur E, et al. Among authors: nicholls aw. Metabolites. 2020 Dec 30;11(1):18. doi: 10.3390/metabo11010018. Metabolites. 2020. PMID: 33396723 Free PMC article.

6

Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse.

Roberts LD, Hassall DG, Winegar DA, Haselden JN, Nicholls AW, Griffin JL. Roberts LD, et al. Among authors: nicholls aw. Genome Med. 2009 Dec 7;1(12):115. doi: 10.1186/gm115. Genome Med. 2009. PMID: 19968882 Free PMC article.

7

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue.

Roberts LD, Murray AJ, Menassa D, Ashmore T, Nicholls AW, Griffin JL. Roberts LD, et al. Among authors: nicholls aw. Genome Biol. 2011 Aug 11;12(8):R75. doi: 10.1186/gb-2011-12-8-r75. Genome Biol. 2011. PMID: 21843327 Free PMC article.

8

Metabolomics dataset of PPAR-pan treated rat liver.

Ament Z, West JA, Stanley E, Li X, Ashmore T, Roberts LD, Wright J, Nicholls AW, Griffin JL. Ament Z, et al. Among authors: nicholls aw. Data Brief. 2016 May 10;8:196-202. doi: 10.1016/j.dib.2016.05.002. eCollection 2016 Sep. Data Brief. 2016. PMID: 27331087 Free PMC article.

9

Metabolic phenotyping of a model of adipocyte differentiation.

Roberts LD, Virtue S, Vidal-Puig A, Nicholls AW, Griffin JL. Roberts LD, et al. Among authors: nicholls aw. Physiol Genomics. 2009 Oct 7;39(2):109-19. doi: 10.1152/physiolgenomics.90365.2008. Epub 2009 Jul 14. Physiol Genomics. 2009. PMID: 19602617 Free PMC article.

10

Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe.

Griffin JL, Nicholls AW, Keun HC, Mortishire-Smith RJ, Nicholson JK, Kuehn T. Griffin JL, et al. Among authors: nicholls aw. Analyst. 2002 May;127(5):582-4. doi: 10.1039/b201207c. Analyst. 2002. PMID: 12081031

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