Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes.
Yuan H, Lanting L, Xu ZG, Li SL, Swiderski P, Putta S, Jonnalagadda M, Kato M, Natarajan R.
Yuan H, et al. Among authors: natarajan r.
Am J Physiol Renal Physiol. 2008 Aug;295(2):F605-17. doi: 10.1152/ajprenal.90268.2008. Epub 2008 Jun 18.
Am J Physiol Renal Physiol. 2008.
PMID: 18562637
Free PMC article.
We previously showed that the 12/15-lipoxygenase (12/15-LO) pathway of arachidonate acid metabolism is involved in multiple events related to diabetic nephropathy (DN), including glomerular hypertrophy and extracellular matrix deposition (Kang SW, Adler SG, Nast CC, LaPage J, Gu …
We previously showed that the 12/15-lipoxygenase (12/15-LO) pathway of arachidonate acid metabolism is involved in multiple events related t …