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A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent assay-based technology.
Alifrangis M, Enosse S, Pearce R, Drakeley C, Roper C, Khalil IF, Nkya WM, Rønn AM, Theander TG, Bygbjerg IC. Alifrangis M, et al. Among authors: roper c. Am J Trop Med Hyg. 2005 Feb;72(2):155-62. Am J Trop Med Hyg. 2005. PMID: 15741552 Free article.
High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581.
Gesase S, Gosling RD, Hashim R, Ord R, Naidoo I, Madebe R, Mosha JF, Joho A, Mandia V, Mrema H, Mapunda E, Savael Z, Lemnge M, Mosha FW, Greenwood B, Roper C, Chandramohan D. Gesase S, et al. Among authors: roper c. PLoS One. 2009;4(2):e4569. doi: 10.1371/journal.pone.0004569. Epub 2009 Feb 24. PLoS One. 2009. PMID: 19238219 Free PMC article. Clinical Trial.
Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy.
Mbacham WF, Evehe MS, Netongo PM, Ateh IA, Mimche PN, Ajua A, Nji AM, Irenee D, Echouffo-Tcheugui JB, Tawe B, Hallett R, Roper C, Targett G, Greenwood B. Mbacham WF, et al. Among authors: roper c. Malar J. 2010 Jan 27;9:34. doi: 10.1186/1475-2875-9-34. Malar J. 2010. PMID: 20105282 Free PMC article. Clinical Trial.
High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children.
Mombo-Ngoma G, Oyakhirome S, Ord R, Gabor JJ, Greutélaers KC, Profanter K, Greutélaers B, Kurth F, Lell B, Kun JF, Issifou S, Roper C, Kremsner PG, Grobusch MP. Mombo-Ngoma G, et al. Among authors: roper c. Malar J. 2011 May 14;10:123. doi: 10.1186/1475-2875-10-123. Malar J. 2011. PMID: 21569596 Free PMC article. Clinical Trial.
311 results