Chrzanowska-Lightowlers ZM - Search Results

1

A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression.

Wilson WC, Hornig-Do HT, Bruni F, Chang JH, Jourdain AA, Martinou JC, Falkenberg M, Spåhr H, Larsson NG, Lewis RJ, Hewitt L, Baslé A, Cross HE, Tong L, Lebel RR, Crosby AH, Chrzanowska-Lightowlers ZM, Lightowlers RN. Wilson WC, et al. Hum Mol Genet. 2014 Dec 1;23(23):6345-55. doi: 10.1093/hmg/ddu352. Epub 2014 Jul 9. Hum Mol Genet. 2014. PMID: 25008111 Free PMC article.

2

Investigation of a pathogenic mtDNA microdeletion reveals a translation-dependent deadenylation decay pathway in human mitochondria.

Temperley RJ, Seneca SH, Tonska K, Bartnik E, Bindoff LA, Lightowlers RN, Chrzanowska-Lightowlers ZM. Temperley RJ, et al. Hum Mol Genet. 2003 Sep 15;12(18):2341-8. doi: 10.1093/hmg/ddg238. Epub 2003 Jul 22. Hum Mol Genet. 2003. PMID: 12915481

3

Functional polypeptides can be synthesized from human mitochondrial transcripts lacking termination codons.

Chrzanowska-Lightowlers ZM, Temperley RJ, Smith PM, Seneca SH, Lightowlers RN. Chrzanowska-Lightowlers ZM, et al. Biochem J. 2004 Feb 1;377(Pt 3):725-31. doi: 10.1042/BJ20031556. Biochem J. 2004. PMID: 14585098 Free PMC article.

4

Messenger RNA stability in mitochondria: different means to an end.

Gagliardi D, Stepien PP, Temperley RJ, Lightowlers RN, Chrzanowska-Lightowlers ZM. Gagliardi D, et al. Trends Genet. 2004 Jun;20(6):260-7. doi: 10.1016/j.tig.2004.04.006. Trends Genet. 2004. PMID: 15145579 Review.

5

Sporadic mitochondrial myopathy due to a new mutation in the mitochondrial tRNASer(UCN) gene.

Bidooki S, Jackson MJ, Johnson MA, Chrzanowska-Lightowlers ZM, Taylor RW, Venables G, Lightowlers RN, Turnbull DM, Bindoff LA. Bidooki S, et al. Neuromuscul Disord. 2004 Jul;14(7):417-20. doi: 10.1016/j.nmd.2004.03.004. Neuromuscul Disord. 2004. PMID: 15210164

6

Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells.

Kolesnikova OA, Entelis NS, Jacquin-Becker C, Goltzene F, Chrzanowska-Lightowlers ZM, Lightowlers RN, Martin RP, Tarassov I. Kolesnikova OA, et al. Hum Mol Genet. 2004 Oct 15;13(20):2519-34. doi: 10.1093/hmg/ddh267. Epub 2004 Aug 18. Hum Mol Genet. 2004. PMID: 15317755

7

Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability.

Seal R, Temperley R, Wilusz J, Lightowlers RN, Chrzanowska-Lightowlers ZM. Seal R, et al. Nucleic Acids Res. 2005 Jan 14;33(1):376-87. doi: 10.1093/nar/gki169. Print 2005. Nucleic Acids Res. 2005. PMID: 15653638 Free PMC article.

8

Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants.

Pye D, Kyriakouli DS, Taylor GA, Johnson R, Elstner M, Meunier B, Chrzanowska-Lightowlers ZM, Taylor RW, Turnbull DM, Lightowlers RN. Pye D, et al. Nucleic Acids Res. 2006 Aug 2;34(13):e95. doi: 10.1093/nar/gkl516. Nucleic Acids Res. 2006. PMID: 16885236 Free PMC article.

9

How do mammalian mitochondria synthesize proteins?

Rorbach J, Soleimanpour-Lichaei R, Lightowlers RN, Chrzanowska-Lightowlers ZM. Rorbach J, et al. Biochem Soc Trans. 2007 Nov;35(Pt 5):1290-1. doi: 10.1042/BST0351290. Biochem Soc Trans. 2007. PMID: 17956332 Review.

10

Overexpression of human mitochondrial valyl tRNA synthetase can partially restore levels of cognate mt-tRNAVal carrying the pathogenic C25U mutation.

Rorbach J, Yusoff AA, Tuppen H, Abg-Kamaludin DP, Chrzanowska-Lightowlers ZM, Taylor RW, Turnbull DM, McFarland R, Lightowlers RN. Rorbach J, et al. Nucleic Acids Res. 2008 May;36(9):3065-74. doi: 10.1093/nar/gkn147. Epub 2008 Apr 8. Nucleic Acids Res. 2008. PMID: 18400783 Free PMC article.

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