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The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events.
J Virol. 2014 Sep;88(18):10803-12. doi: 10.1128/JVI.00320-14. Epub 2014 Jul 9.
J Virol. 2014.
PMID: 25008921
Free PMC article.
A combination HIV reporter virus system for measuring post-entry event efficiency and viral outcome in primary CD4+ T cell subsets.
Tilton CA, Tabler CO, Lucera MB, Marek SL, Haqqani AA, Tilton JC.
Tilton CA, et al. Among authors: lucera mb.
J Virol Methods. 2014 Jan;195:164-9. doi: 10.1016/j.jviromet.2013.08.029. Epub 2013 Sep 8.
J Virol Methods. 2014.
PMID: 24025341
Free PMC article.
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CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression.
Tabler CO, Lucera MB, Haqqani AA, McDonald DJ, Migueles SA, Connors M, Tilton JC.
Tabler CO, et al. Among authors: lucera mb.
J Virol. 2014 May;88(9):4976-86. doi: 10.1128/JVI.00324-14. Epub 2014 Feb 19.
J Virol. 2014.
PMID: 24554663
Free PMC article.
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HIV signaling through CD4 and CCR5 activates Rho family GTPases that are required for optimal infection of primary CD4+ T cells.
Lucera MB, Fleissner Z, Tabler CO, Schlatzer DM, Troyer Z, Tilton JC.
Lucera MB, et al.
Retrovirology. 2017 Jan 24;14(1):4. doi: 10.1186/s12977-017-0328-7.
Retrovirology. 2017.
PMID: 28114951
Free PMC article.
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