Ramesh C - Search Results

1

GPER-targeted, 99mTc-labeled, nonsteroidal ligands demonstrate selective tumor imaging and in vivo estrogen binding.

Nayak TK, Ramesh C, Hathaway HJ, Norenberg JP, Arterburn JB, Prossnitz ER. Nayak TK, et al. Among authors: ramesh c. Mol Cancer Res. 2014 Nov;12(11):1635-43. doi: 10.1158/1541-7786.MCR-14-0289. Epub 2014 Jul 16. Mol Cancer Res. 2014. PMID: 25030373 Free PMC article.

2

Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30.

Revankar CM, Mitchell HD, Field AS, Burai R, Corona C, Ramesh C, Sklar LA, Arterburn JB, Prossnitz ER. Revankar CM, et al. Among authors: ramesh c. ACS Chem Biol. 2007 Aug 17;2(8):536-44. doi: 10.1021/cb700072n. Epub 2007 Jul 27. ACS Chem Biol. 2007. PMID: 17655271

3

Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers.

Nayak TK, Hathaway HJ, Ramesh C, Arterburn JB, Dai D, Sklar LA, Norenberg JP, Prossnitz ER. Nayak TK, et al. Among authors: ramesh c. J Nucl Med. 2008 Jun;49(6):978-86. doi: 10.2967/jnumed.107.048546. Epub 2008 May 15. J Nucl Med. 2008. PMID: 18483091 Free PMC article.

4

In vivo effects of a GPR30 antagonist.

Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. Dennis MK, et al. Among authors: ramesh c. Nat Chem Biol. 2009 Jun;5(6):421-7. doi: 10.1038/nchembio.168. Nat Chem Biol. 2009. PMID: 19430488 Free PMC article.

5

Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30.

Ramesh C, Nayak TK, Burai R, Dennis MK, Hathaway HJ, Sklar LA, Prossnitz ER, Arterburn JB. Ramesh C, et al. J Med Chem. 2010 Feb 11;53(3):1004-14. doi: 10.1021/jm9011802. J Med Chem. 2010. PMID: 20041667 Free PMC article.

6

Influence of charge on cell permeability and tumor imaging of GPR30-targeted 111in-labeled nonsteroidal imaging agents.

Nayak TK, Dennis MK, Ramesh C, Burai R, Atcher RW, Sklar LA, Norenberg JP, Hathaway HJ, Arterburn JB, Prossnitz ER. Nayak TK, et al. Among authors: ramesh c. ACS Chem Biol. 2010 Jul 16;5(7):681-90. doi: 10.1021/cb1000636. ACS Chem Biol. 2010. PMID: 20486699 Free PMC article.

7

Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity.

Dennis MK, Field AS, Burai R, Ramesh C, Petrie WK, Bologa CG, Oprea TI, Yamaguchi Y, Hayashi S, Sklar LA, Hathaway HJ, Arterburn JB, Prossnitz ER. Dennis MK, et al. Among authors: ramesh c. J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):358-66. doi: 10.1016/j.jsbmb.2011.07.002. Epub 2011 Jul 14. J Steroid Biochem Mol Biol. 2011. PMID: 21782022 Free PMC article.

8

Synthesis and characterization of tricarbonyl-Re/Tc(I) chelate probes targeting the G protein-coupled estrogen receptor GPER/GPR30.

Burai R, Ramesh C, Nayak TK, Dennis MK, Bryant BK, Prossnitz ER, Arterburn JB. Burai R, et al. Among authors: ramesh c. PLoS One. 2012;7(10):e46861. doi: 10.1371/journal.pone.0046861. Epub 2012 Oct 15. PLoS One. 2012. PMID: 23077529 Free PMC article.

9

A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling.

Revankar CM, Bologa CG, Pepermans RA, Sharma G, Petrie WK, Alcon SN, Field AS, Ramesh C, Parker MA, Savchuk NP, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. Revankar CM, et al. Among authors: ramesh c. Cell Chem Biol. 2019 Dec 19;26(12):1692-1702.e5. doi: 10.1016/j.chembiol.2019.10.009. Epub 2019 Nov 6. Cell Chem Biol. 2019. PMID: 31706983 Free PMC article.

10

Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates.

Ramesh C, Bryant B, Nayak T, Revankar CM, Anderson T, Carlson KE, Katzenellenbogen JA, Sklar LA, Norenberg JP, Prossnitz ER, Arterburn JB. Ramesh C, et al. J Am Chem Soc. 2006 Nov 15;128(45):14476-7. doi: 10.1021/ja066360p. J Am Chem Soc. 2006. PMID: 17090028 Free PMC article.

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