General IJ - Search Results

1

Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis.

LaRusch J, Jung J, General IJ, Lewis MD, Park HW, Brand RE, Gelrud A, Anderson MA, Banks PA, Conwell D, Lawrence C, Romagnuolo J, Baillie J, Alkaade S, Cote G, Gardner TB, Amann ST, Slivka A, Sandhu B, Aloe A, Kienholz ML, Yadav D, Barmada MM, Bahar I, Lee MG, Whitcomb DC; North American Pancreatitis Study Group. LaRusch J, et al. Among authors: general ij. PLoS Genet. 2014 Jul 17;10(7):e1004376. doi: 10.1371/journal.pgen.1004376. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25033378 Free PMC article.

2

ATPase subdomain IA is a mediator of interdomain allostery in Hsp70 molecular chaperones.

General IJ, Liu Y, Blackburn ME, Mao W, Gierasch LM, Bahar I. General IJ, et al. PLoS Comput Biol. 2014 May 15;10(5):e1003624. doi: 10.1371/journal.pcbi.1003624. eCollection 2014 May. PLoS Comput Biol. 2014. PMID: 24831085 Free PMC article.

3

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer.

Lui VW, Peyser ND, Ng PK, Hritz J, Zeng Y, Lu Y, Li H, Wang L, Gilbert BR, General IJ, Bahar I, Ju Z, Wang Z, Pendleton KP, Xiao X, Du Y, Vries JK, Hammerman PS, Garraway LA, Mills GB, Johnson DE, Grandis JR. Lui VW, et al. Among authors: general ij. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1114-9. doi: 10.1073/pnas.1319551111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395800 Free PMC article.

4

Dynamic Modulation of Binding Affinity as a Mechanism for Regulating Interferon Signaling.

Li H, Sharma N, General IJ, Schreiber G, Bahar I. Li H, et al. Among authors: general ij. J Mol Biol. 2017 Aug 4;429(16):2571-2589. doi: 10.1016/j.jmb.2017.06.011. Epub 2017 Jun 23. J Mol Biol. 2017. PMID: 28648616 Free PMC article.

5

Absolute free energy of binding of avidin/biotin, revisited.

General IJ, Dragomirova R, Meirovitch H. General IJ, et al. J Phys Chem B. 2012 Jun 14;116(23):6628-36. doi: 10.1021/jp212276m. Epub 2012 Feb 27. J Phys Chem B. 2012. PMID: 22300239 Free PMC article.

6

New method for calculating the absolute free energy of binding: the effect of a mobile loop on the avidin/biotin complex.

General IJ, Dragomirova R, Meirovitch H. General IJ, et al. J Phys Chem B. 2011 Jan 13;115(1):168-75. doi: 10.1021/jp1076752. Epub 2010 Dec 15. J Phys Chem B. 2011. PMID: 21158467 Free PMC article.

7

Relative stability of the open and closed conformations of the active site loop of streptavidin.

General IJ, Meirovitch H. General IJ, et al. J Chem Phys. 2011 Jan 14;134(2):025104. doi: 10.1063/1.3521267. J Chem Phys. 2011. PMID: 21241152 Free PMC article.

8

Physical interactions driving the activation/inhibition of calcium/calmodulin dependent protein kinase II.

Asciutto EK, Pantano S, General IJ. Asciutto EK, et al. Among authors: general ij. J Mol Graph Model. 2021 Jun;105:107875. doi: 10.1016/j.jmgm.2021.107875. Epub 2021 Feb 28. J Mol Graph Model. 2021. PMID: 33711790

9

Sodium perchlorate effects on the helical stability of a mainly alanine peptide.

Asciutto EK, General IJ, Xiong K, Asher SA, Madura JD. Asciutto EK, et al. Among authors: general ij. Biophys J. 2010 Jan 20;98(2):186-96. doi: 10.1016/j.bpj.2009.10.013. Biophys J. 2010. PMID: 20338840 Free PMC article.

10

Calculation of the Absolute Free Energy of Binding and Related Entropies with the HSMD-TI Method: The FKBP12-L8 Complex.

General IJ, Dragomirova R, Meirovitch H. General IJ, et al. J Chem Theory Comput. 2011 Oct 27;7(12):4196-4207. doi: 10.1021/ct2004897. J Chem Theory Comput. 2011. PMID: 22328868 Free PMC article.

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