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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling.
Thai LM, O'Reilly L, Reibe-Pal S, Sue N, Holliday H, Small L, Schmitz-Peiffer C, Dhenni R, Wang-Wei Tsai V, Norris N, Yau B, Zhang X, Lee K, Yan C, Shi YC, Kebede MA, Brink R, Cooney GJ, Irvine KM, Breit SN, Phan TG, Swarbrick A, Biden TJ. Thai LM, et al. Among authors: kebede ma. iScience. 2023 Mar 22;26(4):106477. doi: 10.1016/j.isci.2023.106477. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091234 Free PMC article.
Zinc, insulin, and the liver: a ménage à trois.
O'Halloran TV, Kebede M, Philips SJ, Attie AD. O'Halloran TV, et al. J Clin Invest. 2013 Oct;123(10):4136-9. doi: 10.1172/JCI72325. Epub 2013 Sep 24. J Clin Invest. 2013. PMID: 24051373 Free PMC article.
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.
Kebede MA, Oler AT, Gregg T, Balloon AJ, Johnson A, Mitok K, Rabaglia M, Schueler K, Stapleton D, Thorstenson C, Wrighton L, Floyd BJ, Richards O, Raines S, Eliceiri K, Seidah NG, Rhodes C, Keller MP, Coon JL, Audhya A, Attie AD. Kebede MA, et al. J Clin Invest. 2014 Oct;124(10):4240-56. doi: 10.1172/JCI74072. Epub 2014 Aug 26. J Clin Invest. 2014. PMID: 25157818 Free PMC article.
The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, Baliga NS, Smith LM, Broman KW, Yandell BS, Kendziorski C, Attie AD. Keller MP, et al. Among authors: kebede ma. PLoS Genet. 2016 Dec 9;12(12):e1006466. doi: 10.1371/journal.pgen.1006466. eCollection 2016 Dec. PLoS Genet. 2016. PMID: 27935966 Free PMC article.
What the BTBR/J mouse has taught us about diabetes and diabetic complications.
Keller MP, Hudkins KL, Shalev A, Bhatnagar S, Kebede MA, Merrins MJ, Davis DB, Alpers CE, Kimple ME, Attie AD. Keller MP, et al. Among authors: kebede ma. iScience. 2023 Jun 7;26(7):107036. doi: 10.1016/j.isci.2023.107036. eCollection 2023 Jul 21. iScience. 2023. PMID: 37360692 Free PMC article. Review.
ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation.
Stöckli J, Zadoorian A, Cooke KC, Deshpande V, Yau B, Herrmann G, Kebede MA, Humphrey SJ, James DE. Stöckli J, et al. Among authors: kebede ma. Mol Metab. 2019 Jul;25:83-94. doi: 10.1016/j.molmet.2019.05.002. Epub 2019 May 6. Mol Metab. 2019. PMID: 31105056 Free PMC article.
A fluorescent timer reporter enables sorting of insulin secretory granules by age.
Yau B, Hays L, Liang C, Laybutt DR, Thomas HE, Gunton JE, Williams L, Hawthorne WJ, Thorn P, Rhodes CJ, Kebede MA. Yau B, et al. Among authors: kebede ma. J Biol Chem. 2020 Jul 3;295(27):8901-8911. doi: 10.1074/jbc.RA120.012432. Epub 2020 Apr 27. J Biol Chem. 2020. PMID: 32341128 Free PMC article.
Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Yau B, Naghiloo S, Diaz-Vegas A, Carr AV, Van Gerwen J, Needham EJ, Jevon D, Chen SY, Hoehn KL, Brandon AE, Macia L, Cooney GJ, Shortreed MR, Smith LM, Keller MP, Thorn P, Larance M, James DE, Humphrey SJ, Kebede MA. Yau B, et al. Among authors: kebede ma. iScience. 2021 Sep 9;24(10):103099. doi: 10.1016/j.isci.2021.103099. eCollection 2021 Oct 22. iScience. 2021. PMID: 34622154 Free PMC article.
76 results