Lee AV - Search Results

1

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.

Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Gough AH, et al. Among authors: lee av. PLoS One. 2014 Jul 18;9(7):e102678. doi: 10.1371/journal.pone.0102678. eCollection 2014. PLoS One. 2014. PMID: 25036749 Free PMC article.

2

Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients.

Wang P, Bahreini A, Gyanchandani R, Lucas PC, Hartmaier RJ, Watters RJ, Jonnalagadda AR, Trejo Bittar HE, Berg A, Hamilton RL, Kurland BF, Weiss KR, Mathew A, Leone JP, Davidson NE, Nikiforova MN, Brufsky AM, Ambros TF, Stern AM, Puhalla SL, Lee AV, Oesterreich S. Wang P, et al. Among authors: lee av. Clin Cancer Res. 2016 Mar 1;22(5):1130-7. doi: 10.1158/1078-0432.CCR-15-1534. Epub 2015 Oct 23. Clin Cancer Res. 2016. PMID: 26500237 Free PMC article.

3

High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.

Delgado E, Boisen MM, Laskey R, Chen R, Song C, Sallit J, Yochum ZA, Andersen CL, Sikora MJ, Wagner J, Safe S, Elishaev E, Lee A, Edwards RP, Haluska P, Tseng G, Schurdak M, Oesterreich S. Delgado E, et al. Gynecol Oncol. 2016 May;141(2):348-356. doi: 10.1016/j.ygyno.2016.02.030. Epub 2016 Mar 11. Gynecol Oncol. 2016. PMID: 26946093 Free PMC article.

4

Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.

Erdem C, Nagle AM, Casa AJ, Litzenburger BC, Wang YF, Taylor DL, Lee AV, Lezon TR. Erdem C, et al. Among authors: lee av. Mol Cell Proteomics. 2016 Sep;15(9):3045-57. doi: 10.1074/mcp.M115.057729. Epub 2016 Jun 30. Mol Cell Proteomics. 2016. PMID: 27364358 Free PMC article.

5

Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.

Spagnolo DM, Gyanchandani R, Al-Kofahi Y, Stern AM, Lezon TR, Gough A, Meyer DE, Ginty F, Sarachan B, Fine J, Lee AV, Taylor DL, Chennubhotla SC. Spagnolo DM, et al. Among authors: lee av. J Pathol Inform. 2016 Nov 29;7:47. doi: 10.4103/2153-3539.194839. eCollection 2016. J Pathol Inform. 2016. PMID: 27994939 Free PMC article.

6

Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models.

Bahreini A, Li Z, Wang P, Levine KM, Tasdemir N, Cao L, Weir HM, Puhalla SL, Davidson NE, Stern AM, Chu D, Park BH, Lee AV, Oesterreich S. Bahreini A, et al. Among authors: lee av. Breast Cancer Res. 2017 May 23;19(1):60. doi: 10.1186/s13058-017-0851-4. Breast Cancer Res. 2017. PMID: 28535794 Free PMC article.

7

Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images.

Spagnolo DM, Al-Kofahi Y, Zhu P, Lezon TR, Gough A, Stern AM, Lee AV, Ginty F, Sarachan B, Taylor DL, Chennubhotla SC. Spagnolo DM, et al. Among authors: lee av. Cancer Res. 2017 Nov 1;77(21):e71-e74. doi: 10.1158/0008-5472.CAN-17-0676. Cancer Res. 2017. PMID: 29092944 Free PMC article.

8

Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.

Jia S, Miedel MT, Ngo M, Hessenius R, Chen N, Wang P, Bahreini A, Li Z, Ding Z, Shun TY, Zuckerman DM, Taylor DL, Puhalla SL, Lee AV, Oesterreich S, Stern AM. Jia S, et al. Among authors: lee av. Oncology. 2018;94(3):176-189. doi: 10.1159/000485510. Epub 2018 Jan 6. Oncology. 2018. PMID: 29306943 Free PMC article.

9

Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised.

Sannino S, Yates ME, Schurdak ME, Oesterreich S, Lee AV, Wipf P, Brodsky JL. Sannino S, et al. Among authors: lee av. Elife. 2021 Jun 28;10:e64977. doi: 10.7554/eLife.64977. Elife. 2021. PMID: 34180400 Free PMC article.

10

Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.

Erdem C, Lee AV, Taylor DL, Lezon TR. Erdem C, et al. Among authors: lee av. PLoS Comput Biol. 2021 Jun 30;17(6):e1009125. doi: 10.1371/journal.pcbi.1009125. eCollection 2021 Jun. PLoS Comput Biol. 2021. PMID: 34191793 Free PMC article.

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