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Bispecific small molecule-antibody conjugate targeting prostate cancer.
Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG. Kim CH, et al. Among authors: lawson br. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17796-801. doi: 10.1073/pnas.1316026110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127589 Free PMC article.
A CXCR4-targeted site-specific antibody-drug conjugate.
Kularatne SA, Deshmukh V, Ma J, Tardif V, Lim RK, Pugh HM, Sun Y, Manibusan A, Sellers AJ, Barnett RS, Srinagesh S, Forsyth JS, Hassenpflug W, Tian F, Javahishvili T, Felding-Habermann B, Lawson BR, Kazane SA, Schultz PG. Kularatne SA, et al. Among authors: lawson br. Angew Chem Int Ed Engl. 2014 Oct 27;53(44):11863-7. doi: 10.1002/anie.201408103. Epub 2014 Sep 11. Angew Chem Int Ed Engl. 2014. PMID: 25213874 Free PMC article.
Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers.
Cao Y, Axup JY, Ma JS, Wang RE, Choi S, Tardif V, Lim RK, Pugh HM, Lawson BR, Welzel G, Kazane SA, Sun Y, Tian F, Srinagesh S, Javahishvili T, Schultz PG, Kim CH. Cao Y, et al. Among authors: lawson br. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7022-7. doi: 10.1002/anie.201500799. Epub 2015 Apr 27. Angew Chem Int Ed Engl. 2015. PMID: 25919418 Free PMC article.
An immunosuppressive antibody-drug conjugate.
Wang RE, Liu T, Wang Y, Cao Y, Du J, Luo X, Deshmukh V, Kim CH, Lawson BR, Tremblay MS, Young TS, Kazane SA, Wang F, Schultz PG. Wang RE, et al. Among authors: lawson br. J Am Chem Soc. 2015 Mar 11;137(9):3229-32. doi: 10.1021/jacs.5b00620. Epub 2015 Feb 27. J Am Chem Soc. 2015. PMID: 25699419 Free PMC article.
A regenerative approach to the treatment of multiple sclerosis.
Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL. Deshmukh VA, et al. Among authors: lawson br. Nature. 2013 Oct 17;502(7471):327-332. doi: 10.1038/nature12647. Epub 2013 Oct 9. Nature. 2013. PMID: 24107995 Free PMC article.
Transmethylation in immunity and autoimmunity.
Lawson BR, Eleftheriadis T, Tardif V, Gonzalez-Quintial R, Baccala R, Kono DH, Theofilopoulos AN. Lawson BR, et al. Clin Immunol. 2012 Apr;143(1):8-21. doi: 10.1016/j.clim.2011.10.007. Epub 2011 Dec 24. Clin Immunol. 2012. PMID: 22364920 Free PMC article. Review.
PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D. Gavin AL, et al. Among authors: lawson br. Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13. Nat Immunol. 2018. PMID: 30111894 Free PMC article.
64 results