Lam Y - Search Results

1

Modest CaV1.342-selective inhibition by compound 8 is β-subunit dependent.

Huang H, Ng CY, Yu D, Zhai J, Lam Y, Soong TW. Huang H, et al. Among authors: lam y. Nat Commun. 2014 Jul 24;5:4481. doi: 10.1038/ncomms5481. Nat Commun. 2014. PMID: 25057870 Free PMC article.

2

Fluorogenic probes to monitor cytosolic phospholipase A₂ activity.

Ng CY, Kwok TX, Tan FC, Low CM, Lam Y. Ng CY, et al. Among authors: lam y. Chem Commun (Camb). 2017 Feb 2;53(11):1813-1816. doi: 10.1039/c6cc09305a. Chem Commun (Camb). 2017. PMID: 28106899

3

A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A₂.

Ng CY, Kannan S, Chen YJ, Tan FCK, Ong WY, Go ML, Verma CS, Low CM, Lam Y. Ng CY, et al. Among authors: lam y. Sci Rep. 2017 Oct 20;7(1):13683. doi: 10.1038/s41598-017-13996-8. Sci Rep. 2017. PMID: 29057981 Free PMC article.

4

Affinity-Driven Covalent Modulator of the Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Cascade.

Chern J, Lu CP, Fang Z, Chang CM, Hua KF, Chen YT, Ng CY, Chen YS, Lam Y, Wu SH. Chern J, et al. Among authors: lam y. Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7040-7045. doi: 10.1002/anie.201801618. Epub 2018 May 14. Angew Chem Int Ed Engl. 2018. PMID: 29664161

5

Traceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels.

Kong KH, Chen Y, Ma X, Chui WK, Lam Y. Kong KH, et al. Among authors: lam y. J Comb Chem. 2004 Nov-Dec;6(6):928-33. doi: 10.1021/cc049910t. J Comb Chem. 2004. PMID: 15530120

6

Mapping the high-affinity binding domain of 5-substituted benzimidazoles to the proximal N-terminus of the GluN2B subunit of the NMDA receptor.

Wee XK, Ng KS, Leung HW, Cheong YP, Kong KH, Ng FM, Soh W, Lam Y, Low CM. Wee XK, et al. Among authors: lam y. Br J Pharmacol. 2010 Jan 1;159(2):449-61. doi: 10.1111/j.1476-5381.2009.00549.x. Epub 2010 Jan 15. Br J Pharmacol. 2010. PMID: 20082612 Free PMC article.

7

Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 2-{6-[2-(5-phenyl-4H-{1,2,4]triazol-3-ylsulfanyl)acetylamino]benzothiazol-2-ylsulfanyl}acetamide scaffold.

Samanta S, Lim TL, Lam Y. Samanta S, et al. Among authors: lam y. ChemMedChem. 2013 Jun;8(6):994-1001. doi: 10.1002/cmdc.201300114. Epub 2013 Apr 25. ChemMedChem. 2013. PMID: 23619931

8

Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 1,3,4,5-tetrasubstituted 1H-pyrrol-2(5H)-one scaffold.

Gao Y, Samanta S, Cui T, Lam Y. Gao Y, et al. Among authors: lam y. ChemMedChem. 2013 Sep;8(9):1554-60. doi: 10.1002/cmdc.201300244. Epub 2013 Jul 18. ChemMedChem. 2013. PMID: 23868614

9

Divergent Synthesis of Chondroitin Sulfate Disaccharides and Identification of Sulfate Motifs that Inhibit Triple Negative Breast Cancer.

Poh ZW, Gan CH, Lee EJ, Guo S, Yip GW, Lam Y. Poh ZW, et al. Among authors: lam y. Sci Rep. 2015 Sep 24;5:14355. doi: 10.1038/srep14355. Sci Rep. 2015. PMID: 26400608 Free PMC article.

10

Discovery, synthesis, and in vitro evaluation of West Nile virus protease inhibitors based on the 9,10-dihydro-3H,4aH-1,3,9,10a-tetraazaphenanthren-4-one scaffold.

Samanta S, Cui T, Lam Y. Samanta S, et al. Among authors: lam y. ChemMedChem. 2012 Jul;7(7):1210-6. doi: 10.1002/cmdc.201200136. Epub 2012 Apr 30. ChemMedChem. 2012. PMID: 22550001

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