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A novel platform for engineering blood-brain barrier-crossing bispecific biologics.
Farrington GK, Caram-Salas N, Haqqani AS, Brunette E, Eldredge J, Pepinsky B, Antognetti G, Baumann E, Ding W, Garber E, Jiang S, Delaney C, Boileau E, Sisk WP, Stanimirovic DB. Farrington GK, et al. Among authors: pepinsky b. FASEB J. 2014 Nov;28(11):4764-78. doi: 10.1096/fj.14-253369. Epub 2014 Jul 28. FASEB J. 2014. PMID: 25070367
A neutralizing anti-Nogo66 receptor monoclonal antibody reverses inhibition of neurite outgrowth by central nervous system myelin.
Li W, Walus L, Rabacchi SA, Jirik A, Chang E, Schauer J, Zheng BH, Benedetti NJ, Liu BP, Choi E, Worley D, Silvian L, Mo W, Mullen C, Yang W, Strittmatter SM, Sah DW, Pepinsky B, Lee DH. Li W, et al. Among authors: pepinsky b. J Biol Chem. 2004 Oct 15;279(42):43780-8. doi: 10.1074/jbc.M401803200. Epub 2004 Aug 5. J Biol Chem. 2004. PMID: 15297463 Free article.
Engineering potent long-acting variants of the Wnt inhibitor DKK2.
Sopko R, Mugford JW, Lehmann A, Shapiro RI, Rushe M, Kulkarni A, Worrall J, Amatucci J, Wen D, Pederson NE, Minesinger BK, Arndt JW, Pepinsky B. Sopko R, et al. Among authors: pepinsky b. Protein Eng Des Sel. 2017 May 1;30(5):359-372. doi: 10.1093/protein/gzx007. Protein Eng Des Sel. 2017. PMID: 28180900 Free PMC article.
Tat-mediated delivery of heterologous proteins into cells.
Fawell S, Seery J, Daikh Y, Moore C, Chen LL, Pepinsky B, Barsoum J. Fawell S, et al. Among authors: pepinsky b. Proc Natl Acad Sci U S A. 1994 Jan 18;91(2):664-8. doi: 10.1073/pnas.91.2.664. Proc Natl Acad Sci U S A. 1994. PMID: 8290579 Free PMC article.
38 results