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Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.
Pewzner-Jung Y, Tavakoli Tabazavareh S, Grassmé H, Becker KA, Japtok L, Steinmann J, Joseph T, Lang S, Tuemmler B, Schuchman EH, Lentsch AB, Kleuser B, Edwards MJ, Futerman AH, Gulbins E. Pewzner-Jung Y, et al. Among authors: futerman ah. EMBO Mol Med. 2014 Sep;6(9):1205-14. doi: 10.15252/emmm.201404075. EMBO Mol Med. 2014. PMID: 25085879 Free PMC article.
Ceramide synthase 1 is regulated by proteasomal mediated turnover.
Sridevi P, Alexander H, Laviad EL, Pewzner-Jung Y, Hannink M, Futerman AH, Alexander S. Sridevi P, et al. Among authors: futerman ah. Biochim Biophys Acta. 2009 Jul;1793(7):1218-27. doi: 10.1016/j.bbamcr.2009.04.006. Epub 2009 Apr 22. Biochim Biophys Acta. 2009. PMID: 19393694 Free PMC article.
A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy.
Pewzner-Jung Y, Brenner O, Braun S, Laviad EL, Ben-Dor S, Feldmesser E, Horn-Saban S, Amann-Zalcenstein D, Raanan C, Berkutzki T, Erez-Roman R, Ben-David O, Levy M, Holzman D, Park H, Nyska A, Merrill AH Jr, Futerman AH. Pewzner-Jung Y, et al. Among authors: futerman ah. J Biol Chem. 2010 Apr 2;285(14):10911-23. doi: 10.1074/jbc.M109.077610. Epub 2010 Jan 28. J Biol Chem. 2010. PMID: 20110366 Free PMC article.
Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels.
Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J, Raas-Rothschild A, Friedman A, Brügger B, Merrill AH Jr, Futerman AH. Ben-David O, et al. Among authors: futerman ah. J Biol Chem. 2011 Aug 26;286(34):30022-33. doi: 10.1074/jbc.M111.261206. Epub 2011 Jun 24. J Biol Chem. 2011. PMID: 21705317 Free PMC article.
276 results