Bowman RL - Search Results

1

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S.

Sevenich L, Bowman RL, Mason SD, Quail DF, Rapaport F, Elie BT, Brogi E, Brastianos PK, Hahn WC, Holsinger LJ, Massagué J, Leslie CS, Joyce JA. Sevenich L, et al. Among authors: bowman rl. Nat Cell Biol. 2014 Sep;16(9):876-88. doi: 10.1038/ncb3011. Epub 2014 Aug 3. Nat Cell Biol. 2014. PMID: 25086747 Free PMC article.

2

CSF-1R inhibition alters macrophage polarization and blocks glioma progression.

Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. Pyonteck SM, et al. Among authors: bowman rl. Nat Med. 2013 Oct;19(10):1264-72. doi: 10.1038/nm.3337. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056773 Free PMC article.

3

Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma.

Bowman RL, Joyce JA. Bowman RL, et al. Immunotherapy. 2014;6(6):663-6. doi: 10.2217/imt.14.48. Immunotherapy. 2014. PMID: 25041027 No abstract available.

4

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.

Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA. Akkari L, et al. Among authors: bowman rl. Genes Dev. 2016 Jan 15;30(2):220-32. doi: 10.1101/gad.270439.115. Genes Dev. 2016. PMID: 26773004 Free PMC article.

5

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.

Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, Joyce JA. Quail DF, et al. Among authors: bowman rl. Science. 2016 May 20;352(6288):aad3018. doi: 10.1126/science.aad3018. Science. 2016. PMID: 27199435 Free PMC article.

6

STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation.

Yan D, Wang HW, Bowman RL, Joyce JA. Yan D, et al. Among authors: bowman rl. Cell Rep. 2016 Sep 13;16(11):2914-2927. doi: 10.1016/j.celrep.2016.08.035. Cell Rep. 2016. PMID: 27626662 Free PMC article.

7

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies.

Bowman RL, Klemm F, Akkari L, Pyonteck SM, Sevenich L, Quail DF, Dhara S, Simpson K, Gardner EE, Iacobuzio-Donahue CA, Brennan CW, Tabar V, Gutin PH, Joyce JA. Bowman RL, et al. Cell Rep. 2016 Nov 22;17(9):2445-2459. doi: 10.1016/j.celrep.2016.10.052. Epub 2016 Nov 10. Cell Rep. 2016. PMID: 27840052 Free PMC article.

8

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

Kleppe M, Spitzer MH, Li S, Hill CE, Dong L, Papalexi E, De Groote S, Bowman RL, Keller M, Koppikar P, Rapaport FT, Teruya-Feldstein J, Gandara J, Mason CE, Nolan GP, Levine RL. Kleppe M, et al. Among authors: bowman rl. Cell Stem Cell. 2017 Oct 5;21(4):489-501.e7. doi: 10.1016/j.stem.2017.08.011. Epub 2017 Sep 28. Cell Stem Cell. 2017. PMID: 28965767 Free PMC article.

9

Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells.

Klemm F, Maas RR, Bowman RL, Kornete M, Soukup K, Nassiri S, Brouland JP, Iacobuzio-Donahue CA, Brennan C, Tabar V, Gutin PH, Daniel RT, Hegi ME, Joyce JA. Klemm F, et al. Among authors: bowman rl. Cell. 2020 Jun 25;181(7):1643-1660.e17. doi: 10.1016/j.cell.2020.05.007. Epub 2020 May 28. Cell. 2020. PMID: 32470396 Free PMC article.

10

Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment.

Dumas AA, Pomella N, Rosser G, Guglielmi L, Vinel C, Millner TO, Rees J, Aley N, Sheer D, Wei J, Marisetty A, Heimberger AB, Bowman RL, Brandner S, Joyce JA, Marino S. Dumas AA, et al. Among authors: bowman rl. EMBO J. 2020 Aug 3;39(15):e103790. doi: 10.15252/embj.2019103790. Epub 2020 Jun 22. EMBO J. 2020. PMID: 32567735 Free PMC article.

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