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Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death.
Bastos TM, Barbosa MI, da Silva MM, da C Júnior JW, Meira CS, Guimaraes ET, Ellena J, Moreira DR, Batista AA, Soares MB. Bastos TM, et al. Among authors: ellena j. Antimicrob Agents Chemother. 2014 Oct;58(10):6044-55. doi: 10.1128/AAC.02765-14. Epub 2014 Aug 4. Antimicrob Agents Chemother. 2014. PMID: 25092707 Free PMC article.
Synthesis, characterization, X-ray structure and in vitro antimycobacterial and antitumoral activities of Ru(II) phosphine/diimine complexes containing the "SpymMe2" ligand, SpymMe2=4,6-dimethyl-2-mercaptopyrimidine.
do Nascimento FB, Von Poelhsitz G, Pavan FR, Sato DN, Leite CQ, Selistre-de-Araújo HS, Ellena J, Castellano EE, Deflon VM, Batista AA. do Nascimento FB, et al. Among authors: ellena j. J Inorg Biochem. 2008 Sep;102(9):1783-9. doi: 10.1016/j.jinorgbio.2008.05.009. Epub 2008 May 29. J Inorg Biochem. 2008. PMID: 18614238
Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity.
Silva JJ, Guedes PM, Zottis A, Balliano TL, Nascimento Silva FO, França Lopes LG, Ellena J, Oliva G, Andricopulo AD, Franco DW, Silva JS. Silva JJ, et al. Among authors: ellena j. Br J Pharmacol. 2010 May;160(2):260-9. doi: 10.1111/j.1476-5381.2009.00524.x. Epub 2010 Jan 26. Br J Pharmacol. 2010. PMID: 20105182 Free PMC article.
224 results