Aklillu E - Search Results

1

Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment.

Ngaimisi E, Minzi O, Mugusi S, Sasi P, Riedel KD, Suda A, Ueda N, Bakari M, Janabi M, Mugusi F, Bertilsson L, Burhenne J, Aklillu E, Diczfalusy U. Ngaimisi E, et al. Among authors: aklillu e. J Antimicrob Chemother. 2014 Dec;69(12):3311-9. doi: 10.1093/jac/dku286. Epub 2014 Aug 4. J Antimicrob Chemother. 2014. PMID: 25096076

2

Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden.

Aklillu E, Herrlin K, Gustafsson LL, Bertilsson L, Ingelman-Sundberg M. Aklillu E, et al. Pharmacogenetics. 2002 Jul;12(5):375-83. doi: 10.1097/00008571-200207000-00005. Pharmacogenetics. 2002. PMID: 12142727

3

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1.

Aklillu E, Carrillo JA, Makonnen E, Hellman K, Pitarque M, Bertilsson L, Ingelman-Sundberg M. Aklillu E, et al. Mol Pharmacol. 2003 Sep;64(3):659-69. doi: 10.1124/mol.64.3.659. Mol Pharmacol. 2003. PMID: 12920202

4

Xanthine oxidase activity is influenced by environmental factors in Ethiopians.

Aklillu E, Carrillo JA, Makonnen E, Bertilsson L, Ingelman-Sundberg M. Aklillu E, et al. Eur J Clin Pharmacol. 2003 Oct;59(7):533-6. doi: 10.1007/s00228-003-0653-8. Epub 2003 Aug 21. Eur J Clin Pharmacol. 2003. PMID: 12937875

5

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.

Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, Ingelman-Sundberg M. Sim SC, et al. Among authors: aklillu e. Clin Pharmacol Ther. 2006 Jan;79(1):103-13. doi: 10.1016/j.clpt.2005.10.002. Clin Pharmacol Ther. 2006. PMID: 16413245

6

Monoamine metabolites level in CSF is related to the 5-HTT gene polymorphism in treatment-resistant depression.

Kishida I, Aklillu E, Kawanishi C, Bertilsson L, Agren H. Kishida I, et al. Among authors: aklillu e. Neuropsychopharmacology. 2007 Oct;32(10):2143-51. doi: 10.1038/sj.npp.1301336. Epub 2007 Feb 14. Neuropsychopharmacology. 2007. PMID: 17299512

7

CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir.

Josephson F, Allqvist A, Janabi M, Sayi J, Aklillu E, Jande M, Mahindi M, Burhenne J, Bottiger Y, Gustafsson LL, Haefeli WE, Bertilsson L. Josephson F, et al. Among authors: aklillu e. Clin Pharmacol Ther. 2007 May;81(5):708-12. doi: 10.1038/sj.clpt.6100117. Epub 2007 Feb 28. Clin Pharmacol Ther. 2007. PMID: 17329995

8

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans.

Ghotbi R, Christensen M, Roh HK, Ingelman-Sundberg M, Aklillu E, Bertilsson L. Ghotbi R, et al. Among authors: aklillu e. Eur J Clin Pharmacol. 2007 Jun;63(6):537-46. doi: 10.1007/s00228-007-0288-2. Epub 2007 Mar 17. Eur J Clin Pharmacol. 2007. PMID: 17370067

9

Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes.

Djordjevic N, Ghotbi R, Bertilsson L, Jankovic S, Aklillu E. Djordjevic N, et al. Among authors: aklillu e. Eur J Clin Pharmacol. 2008 Apr;64(4):381-5. doi: 10.1007/s00228-007-0438-6. Epub 2007 Dec 22. Eur J Clin Pharmacol. 2008. PMID: 18157525

10

4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians.

Diczfalusy U, Miura J, Roh HK, Mirghani RA, Sayi J, Larsson H, Bodin KG, Allqvist A, Jande M, Kim JW, Aklillu E, Gustafsson LL, Bertilsson L. Diczfalusy U, et al. Among authors: aklillu e. Pharmacogenet Genomics. 2008 Mar;18(3):201-8. doi: 10.1097/FPC.0b013e3282f50ee9. Pharmacogenet Genomics. 2008. PMID: 18300941

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