Le V - Search Results

1

Diminazene or berenil, a classic duplex minor groove binder, binds to G-quadruplexes with low nanomolar dissociation constants and the amidine groups are also critical for G-quadruplex binding.

Zhou J, Le V, Kalia D, Nakayama S, Mikek C, Lewis EA, Sintim HO. Zhou J, et al. Among authors: le v. Mol Biosyst. 2014 Oct;10(10):2724-34. doi: 10.1039/c4mb00359d. Mol Biosyst. 2014. PMID: 25096593

2

Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site.

Lewis EA, Munde M, Wang S, Rettig M, Le V, Machha V, Wilson WD. Lewis EA, et al. Among authors: le v. Nucleic Acids Res. 2011 Dec;39(22):9649-58. doi: 10.1093/nar/gkr699. Epub 2011 Sep 3. Nucleic Acids Res. 2011. PMID: 21890907 Free PMC article.

3

The effect of pyridyl substituents on the thermodynamics of porphyrin binding to G-quadruplex DNA.

Rowland GB, Barnett K, Dupont JI, Akurathi G, Le VH, Lewis EA. Rowland GB, et al. Bioorg Med Chem. 2013 Dec 1;21(23):7515-22. doi: 10.1016/j.bmc.2013.09.036. Epub 2013 Sep 21. Bioorg Med Chem. 2013. PMID: 24148836

4

DSC deconvolution of the structural complexity of c-MYC P1 promoter G-quadruplexes.

Dettler JM, Buscaglia R, Le VH, Lewis EA. Dettler JM, et al. Biophys J. 2011 Mar 16;100(6):1517-25. doi: 10.1016/j.bpj.2011.01.068. Biophys J. 2011. PMID: 21402034 Free PMC article.

5

Bcl-2 promoter sequence G-quadruplex interactions with three planar and non-planar cationic porphyrins: TMPyP4, TMPyP3, and TMPyP2.

Le VH, Nagesh N, Lewis EA. Le VH, et al. PLoS One. 2013 Aug 20;8(8):e72462. doi: 10.1371/journal.pone.0072462. eCollection 2013. PLoS One. 2013. PMID: 23977303 Free PMC article.

6

Role of water in netropsin binding to an A(2)T(2) hairpin DNA site: osmotic stress experiments.

Ramos JP, Le VH, Lewis EA. Ramos JP, et al. J Phys Chem B. 2013 Dec 19;117(50):15958-65. doi: 10.1021/jp408077m. Epub 2013 Dec 5. J Phys Chem B. 2013. PMID: 24274393

7

Thermodynamic investigations of [(phen)2Ru(tatpp)Ru(phen)2](4+) interactions with B-DNA.

Le VH, McGuire MR, Ahuja P, MacDonnell FM, Lewis EA. Le VH, et al. J Phys Chem B. 2015 Jan 8;119(1):65-71. doi: 10.1021/jp509569s. Epub 2014 Dec 16. J Phys Chem B. 2015. PMID: 25437923

8

Calorimetric and spectroscopic investigations of the binding of metallated porphyrins to G-quadruplex DNA.

DuPont JI, Henderson KL, Metz A, Le VH, Emerson JP, Lewis EA. DuPont JI, et al. Biochim Biophys Acta. 2016 May;1860(5):902-909. doi: 10.1016/j.bbagen.2015.09.004. Epub 2015 Sep 9. Biochim Biophys Acta. 2016. PMID: 26363462

9

Recognition and binding of human telomeric G-quadruplex DNA by unfolding protein 1.

Hudson JS, Ding L, Le V, Lewis E, Graves D. Hudson JS, et al. Among authors: le v. Biochemistry. 2014 May 27;53(20):3347-56. doi: 10.1021/bi500351u. Epub 2014 May 15. Biochemistry. 2014. PMID: 24831962 Free PMC article.

10

Exploring substrate binding in homoprotocatechuate 2,3-dioxygenase using isothermal titration calorimetry.

Henderson KL, Le VH, Lewis EA, Emerson JP. Henderson KL, et al. J Biol Inorg Chem. 2012 Oct;17(7):991-4. doi: 10.1007/s00775-012-0929-5. Epub 2012 Aug 23. J Biol Inorg Chem. 2012. PMID: 22915062

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