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Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770.
Gentzsch M, Ren HY, Houck SA, Quinney NL, Cholon DM, Sopha P, Chaudhry IG, Das J, Dokholyan NV, Randell SH, Cyr DM. Gentzsch M, et al. Among authors: quinney nl. Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L550-9. doi: 10.1152/ajplung.00186.2016. Epub 2016 Jul 8. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27402691 Free PMC article.
Nasospheroids permit measurements of CFTR-dependent fluid transport.
Guimbellot JS, Leach JM, Chaudhry IG, Quinney NL, Boyles SE, Chua M, Aban I, Jaspers I, Gentzsch M. Guimbellot JS, et al. Among authors: quinney nl. JCI Insight. 2017 Nov 16;2(22):e95734. doi: 10.1172/jci.insight.95734. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202459 Free PMC article.
Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.
Tomati V, Caci E, Ferrera L, Pesce E, Sondo E, Cholon DM, Quinney NL, Boyles SE, Armirotti A, Ravazzolo R, Galietta LJ, Gentzsch M, Pedemonte N. Tomati V, et al. Among authors: quinney nl. JCI Insight. 2018 Feb 8;3(3):e98699. doi: 10.1172/jci.insight.98699. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415893 Free PMC article.
Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.
Tomati V, Caci E, Ferrera L, Pesce E, Sondo E, Cholon DM, Quinney NL, Boyles SE, Armirotti A, Ravazzolo R, Galietta LJ, Gentzsch M, Pedemonte N. Tomati V, et al. Among authors: quinney nl. JCI Insight. 2019 Apr 4;4(7):e128935. doi: 10.1172/jci.insight.128935. eCollection 2019 Apr 4. JCI Insight. 2019. PMID: 30944255 Free PMC article. No abstract available.
Personalised medicine for non-classic cystic fibrosis resulting from rare CFTR mutations.
McCravy MS, Quinney NL, Cholon DM, Boyles SE, Jensen TJ, Aleksandrov AA, Donaldson SH, Noone PG, Gentzsch M. McCravy MS, et al. Among authors: quinney nl. Eur Respir J. 2020 Jul 30;56(1):2000062. doi: 10.1183/13993003.00062-2020. Print 2020 Jul. Eur Respir J. 2020. PMID: 32265312 Free PMC article. No abstract available.
22 results