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Structural basis of nSH2 regulation and lipid binding in PI3Kα.
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Miller MS, et al. Among authors: allaire m. Oncotarget. 2014 Jul 30;5(14):5198-208. doi: 10.18632/oncotarget.2263. Oncotarget. 2014. PMID: 25105564 Free PMC article.
Solvent minimization induces preferential orientation and crystal clustering in serial micro-crystallography on micro-meshes, in situ plates and on a movable crystal conveyor belt.
Soares AS, Mullen JD, Parekh RM, McCarthy GS, Roessler CG, Jackimowicz R, Skinner JM, Orville AM, Allaire M, Sweet RM. Soares AS, et al. Among authors: allaire m. J Synchrotron Radiat. 2014 Nov;21(Pt 6):1231-9. doi: 10.1107/S1600577514017731. Epub 2014 Oct 9. J Synchrotron Radiat. 2014. PMID: 25343789 Free PMC article.
A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection.
Cole K, Roessler CG, Mulé EA, Benson-Xu EJ, Mullen JD, Le BA, Tieman AM, Birone C, Brown M, Hernandez J, Neff S, Williams D, Allaire M, Orville AM, Sweet RM, Soares AS. Cole K, et al. Among authors: allaire m. PLoS One. 2014 Jul 2;9(7):e101036. doi: 10.1371/journal.pone.0101036. eCollection 2014. PLoS One. 2014. PMID: 24988328 Free PMC article.
Acoustically mounted microcrystals yield high-resolution X-ray structures.
Soares AS, Engel MA, Stearns R, Datwani S, Olechno J, Ellson R, Skinner JM, Allaire M, Orville AM. Soares AS, et al. Among authors: allaire m. Biochemistry. 2011 May 31;50(21):4399-401. doi: 10.1021/bi200549x. Epub 2011 May 9. Biochemistry. 2011. PMID: 21542590 Free PMC article.
146 results