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Page 1
Structural basis of nSH2 regulation and lipid binding in PI3Kα.
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Miller MS, et al. Among authors: bolduc dm. Oncotarget. 2014 Jul 30;5(14):5198-208. doi: 10.18632/oncotarget.2263. Oncotarget. 2014. PMID: 25105564 Free PMC article.
Enzyme-catalyzed expressed protein ligation.
Henager SH, Chu N, Chen Z, Bolduc D, Dempsey DR, Hwang Y, Wells J, Cole PA. Henager SH, et al. Nat Methods. 2016 Nov;13(11):925-927. doi: 10.1038/nmeth.4004. Epub 2016 Sep 26. Nat Methods. 2016. PMID: 27669326 Free PMC article.
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
Chiang MJ, Holbert MA, Kalin JH, Ahn YH, Giddens J, Amin MN, Taylor MS, Collins SL, Chan-Li Y, Waickman A, Hsiao PY, Bolduc D, Leahy DJ, Horton MR, Wang LX, Powell JD, Cole PA. Chiang MJ, et al. J Am Chem Soc. 2014 Mar 5;136(9):3370-3. doi: 10.1021/ja5006674. Epub 2014 Feb 24. J Am Chem Soc. 2014. PMID: 24533830 Free PMC article.
Enzymatic Assays for Studying Intramembrane Proteolysis.
Bolduc DM, Selkoe DJ, Wolfe MS. Bolduc DM, et al. Methods Enzymol. 2017;584:295-308. doi: 10.1016/bs.mie.2016.10.026. Epub 2016 Dec 24. Methods Enzymol. 2017. PMID: 28065268 Free PMC article.
Structure of nicastrin unveils secrets of γ-secretase.
Bolduc DM, Wolfe MS. Bolduc DM, et al. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14643-4. doi: 10.1073/pnas.1416637111. Epub 2014 Sep 29. Proc Natl Acad Sci U S A. 2014. PMID: 25267656 Free PMC article. No abstract available.
The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity.
Nguyen TV, Yao S, Wang Y, Rolfe A, Selvaraj A, Darman R, Ke J, Warmuth M, Smith PG, Larsen NA, Yu L, Zhu P, Fekkes P, Vaillancourt FH, Bolduc DM. Nguyen TV, et al. Among authors: bolduc dm. J Biol Chem. 2019 Nov 8;294(45):16966-16977. doi: 10.1074/jbc.RA119.010126. Epub 2019 Oct 3. J Biol Chem. 2019. PMID: 31582562 Free PMC article.
17 results