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Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML.
Zaitseva L, Murray MY, Shafat MS, Lawes MJ, MacEwan DJ, Bowles KM, Rushworth SA. Zaitseva L, et al. Among authors: murray my. Oncotarget. 2014 Oct 30;5(20):9930-8. doi: 10.18632/oncotarget.2479. Oncotarget. 2014. PMID: 25294819 Free PMC article.
Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells.
Rushworth SA, Pillinger G, Abdul-Aziz A, Piddock R, Shafat MS, Murray MY, Zaitseva L, Lawes MJ, MacEwan DJ, Bowles KM. Rushworth SA, et al. Among authors: murray my. Lancet Haematol. 2015 May;2(5):e204-11. doi: 10.1016/S2352-3026(15)00046-0. Epub 2015 Apr 14. Lancet Haematol. 2015. PMID: 26688095
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