Pfeilschifter J - Search Results

1

The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death.

Pastukhov O, Schwalm S, Zangemeister-Wittke U, Fabbro D, Bornancin F, Japtok L, Kleuser B, Pfeilschifter J, Huwiler A. Pastukhov O, et al. Among authors: pfeilschifter j. Br J Pharmacol. 2014 Dec;171(24):5829-44. doi: 10.1111/bph.12886. Br J Pharmacol. 2014. PMID: 25134723 Free PMC article.

2

New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets.

Huwiler A, Pfeilschifter J. Huwiler A, et al. Among authors: pfeilschifter j. Biochem Pharmacol. 2008 May 15;75(10):1893-900. doi: 10.1016/j.bcp.2007.12.018. Epub 2008 Jan 5. Biochem Pharmacol. 2008. PMID: 18321471 Review.

3

Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner.

Hofmann LP, Ren S, Schwalm S, Pfeilschifter J, Huwiler A. Hofmann LP, et al. Among authors: pfeilschifter j. Biol Chem. 2008 Nov;389(11):1399-407. doi: 10.1515/BC.2008.160. Biol Chem. 2008. PMID: 18783337 Free article.

4

A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation.

Ren S, Xin C, Pfeilschifter J, Huwiler A. Ren S, et al. Among authors: pfeilschifter j. Cell Physiol Biochem. 2010;26(1):97-104. doi: 10.1159/000315110. Epub 2010 May 18. Cell Physiol Biochem. 2010. PMID: 20502009 Free article.

5

Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation.

Schwalm S, Pfeilschifter J, Huwiler A. Schwalm S, et al. Among authors: pfeilschifter j. Br J Pharmacol. 2010 Aug;160(7):1641-51. doi: 10.1111/j.1476-5381.2010.00818.x. Br J Pharmacol. 2010. PMID: 20649568 Free PMC article.

6

Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage.

Huwiler A, Kotelevets N, Xin C, Pastukhov O, Pfeilschifter J, Zangemeister-Wittke U. Huwiler A, et al. Among authors: pfeilschifter j. Br J Pharmacol. 2011 Jan;162(2):532-43. doi: 10.1111/j.1476-5381.2010.01053.x. Br J Pharmacol. 2011. PMID: 20883472 Free PMC article.

7

Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases.

Schwalm S, Pfeilschifter J, Huwiler A. Schwalm S, et al. Among authors: pfeilschifter j. Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):44-9. doi: 10.1111/bcpt.12103. Epub 2013 Jul 15. Basic Clin Pharmacol Toxicol. 2014. PMID: 23789924 Free article. Review.

8

Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts.

Pastukhov O, Schwalm S, Römer I, Zangemeister-Wittke U, Pfeilschifter J, Huwiler A. Pastukhov O, et al. Among authors: pfeilschifter j. Cell Physiol Biochem. 2014;34(1):119-33. doi: 10.1159/000362989. Epub 2014 Jun 16. Cell Physiol Biochem. 2014. PMID: 24977486 Free article.

9

Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis.

Beyer S, Schwalm S, Pfeilschifter J, Huwiler A. Beyer S, et al. Among authors: pfeilschifter j. Cell Physiol Biochem. 2018;47(6):2522-2533. doi: 10.1159/000491625. Epub 2018 Jul 10. Cell Physiol Biochem. 2018. PMID: 29991026 Free article.

10

Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt.

Schwalm S, Erhardt M, Römer I, Pfeilschifter J, Zangemeister-Wittke U, Huwiler A. Schwalm S, et al. Among authors: pfeilschifter j. Int J Mol Sci. 2020 Feb 19;21(4):1396. doi: 10.3390/ijms21041396. Int J Mol Sci. 2020. PMID: 32092937 Free PMC article.

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