Li X - Search Results

1

SIRT1-mediated deacetylation of CRABPII regulates cellular retinoic acid signaling and modulates embryonic stem cell differentiation.

Tang S, Huang G, Fan W, Chen Y, Ward JM, Xu X, Xu Q, Kang A, McBurney MW, Fargo DC, Hu G, Baumgart-Vogt E, Zhao Y, Li X. Tang S, et al. Among authors: li x. Mol Cell. 2014 Sep 18;55(6):843-855. doi: 10.1016/j.molcel.2014.07.011. Epub 2014 Aug 21. Mol Cell. 2014. PMID: 25155613 Free PMC article.

2

SIRT1 deacetylates and positively regulates the nuclear receptor LXR.

Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L. Li X, et al. Mol Cell. 2007 Oct 12;28(1):91-106. doi: 10.1016/j.molcel.2007.07.032. Mol Cell. 2007. PMID: 17936707 Free article.

3

Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

Purushotham A, Schug TT, Xu Q, Surapureddi S, Guo X, Li X. Purushotham A, et al. Among authors: li x. Cell Metab. 2009 Apr;9(4):327-38. doi: 10.1016/j.cmet.2009.02.006. Cell Metab. 2009. PMID: 19356714 Free PMC article.

4

Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.

Schug TT, Xu Q, Gao H, Peres-da-Silva A, Draper DW, Fessler MB, Purushotham A, Li X. Schug TT, et al. Among authors: li x. Mol Cell Biol. 2010 Oct;30(19):4712-21. doi: 10.1128/MCB.00657-10. Epub 2010 Jul 20. Mol Cell Biol. 2010. PMID: 20647536 Free PMC article.

5

Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding.

Purushotham A, Xu Q, Li X. Purushotham A, et al. Among authors: li x. FASEB J. 2012 Feb;26(2):656-67. doi: 10.1096/fj.11-195172. Epub 2011 Oct 17. FASEB J. 2012. PMID: 22006157 Free PMC article.

6

Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.

Purushotham A, Xu Q, Lu J, Foley JF, Yan X, Kim DH, Kemper JK, Li X. Purushotham A, et al. Among authors: li x. Mol Cell Biol. 2012 Apr;32(7):1226-36. doi: 10.1128/MCB.05988-11. Epub 2012 Jan 30. Mol Cell Biol. 2012. PMID: 22290433 Free PMC article.

7

The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status.

Guo X, Kesimer M, Tolun G, Zheng X, Xu Q, Lu J, Sheehan JK, Griffith JD, Li X. Guo X, et al. Among authors: li x. Sci Rep. 2012;2:640. doi: 10.1038/srep00640. Epub 2012 Sep 7. Sci Rep. 2012. PMID: 22962634 Free PMC article.

8

SIRT1 and energy metabolism.

Li X. Li X. Acta Biochim Biophys Sin (Shanghai). 2013 Jan;45(1):51-60. doi: 10.1093/abbs/gms108. Acta Biochim Biophys Sin (Shanghai). 2013. PMID: 23257294 Free PMC article. Review.

9

The ways and means that fine tune Sirt1 activity.

Revollo JR, Li X. Revollo JR, et al. Among authors: li x. Trends Biochem Sci. 2013 Mar;38(3):160-7. doi: 10.1016/j.tibs.2012.12.004. Epub 2013 Feb 7. Trends Biochem Sci. 2013. PMID: 23394938 Free PMC article. Review.

10

Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

Choi SE, Fu T, Seok S, Kim DH, Yu E, Lee KW, Kang Y, Li X, Kemper B, Kemper JK. Choi SE, et al. Among authors: li x. Aging Cell. 2013 Dec;12(6):1062-72. doi: 10.1111/acel.12135. Epub 2013 Aug 11. Aging Cell. 2013. PMID: 23834033 Free PMC article.

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