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Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes.
Saberi M, Bjelica D, Schenk S, Imamura T, Bandyopadhyay G, Li P, Jadhar V, Vargeese C, Wang W, Bowman K, Zhang Y, Polisky B, Olefsky JM. Saberi M, et al. Among authors: schenk s. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1137-46. doi: 10.1152/ajpendo.00158.2009. Epub 2009 Aug 25. Am J Physiol Endocrinol Metab. 2009. PMID: 19706791 Free PMC article.
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity.
Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM. Yoshizaki T, et al. Among authors: schenk s. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E419-28. doi: 10.1152/ajpendo.00417.2009. Epub 2009 Dec 8. Am J Physiol Endocrinol Metab. 2010. PMID: 19996381 Free PMC article.
Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise.
Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Philp A, et al. Among authors: schenk s. J Biol Chem. 2011 Sep 2;286(35):30561-30570. doi: 10.1074/jbc.M111.261685. Epub 2011 Jul 11. J Biol Chem. 2011. PMID: 21757760 Free PMC article.
536 results