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Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue.
Chan KR, Ong EZ, Tan HC, Zhang SL, Zhang Q, Tang KF, Kaliaperumal N, Lim AP, Hibberd ML, Chan SH, Connolly JE, Krishnan MN, Lok SM, Hanson BJ, Lin CN, Ooi EE. Chan KR, et al. Among authors: kaliaperumal n. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2722-7. doi: 10.1073/pnas.1317454111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24550301 Free PMC article.
Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine.
Skibinski DAG, Jones LA, Zhu YO, Xue LW, Au B, Lee B, Naim ANM, Lee A, Kaliaperumal N, Low JGH, Lee LS, Poidinger M, Saudan P, Bachmann M, Ooi EE, Hanson BJ, Novotny-Diermayr V, Matter A, Fairhurst AM, Hibberd ML, Connolly JE. Skibinski DAG, et al. Among authors: kaliaperumal n. Sci Rep. 2018 Dec 20;8(1):18007. doi: 10.1038/s41598-018-36703-7. Sci Rep. 2018. PMID: 30573748 Free PMC article. Clinical Trial.
A multicenter phase II randomized trial of durvalumab (MEDI-4736) versus physician's choice chemotherapy in recurrent ovarian clear cell adenocarcinoma (MOCCA).
Ngoi NY, Heong V, Ow S, Chay WY, Kim HS, Choi CH, Goss G, Goh JC, Tai BC, Lim DG, Kaliaperumal N, Au VB, Connolly JE, Kim JW, Friedlander M, Kim K, Tan DS. Ngoi NY, et al. Among authors: kaliaperumal n. Int J Gynecol Cancer. 2020 Aug;30(8):1239-1242. doi: 10.1136/ijgc-2020-001604. Epub 2020 Jun 25. Int J Gynecol Cancer. 2020. PMID: 32591370 Free PMC article.
Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency.
Tan EE, Hopkins RA, Lim CK, Jamuar SS, Ong C, Thoon KC, Koh MJ, Shin EM, Lian DW, Weerasooriya M, Lee CZ, Soetedjo AAP, Lim CS, Au VB, Chua E, Lee HY, Jones LA, James SS, Kaliaperumal N, Kwok J, Tan ES, Thomas B, Wu LX, Ho L, Fairhurst AM, Ginhoux F, Teo AK, Zhang YL, Ong KH, Yu W, Venkatesh B, Tergaonkar V, Reversade B, Chin KC, Tan AM, Liew WK, Connolly JE. Tan EE, et al. Among authors: kaliaperumal n. J Clin Invest. 2020 Nov 2;130(11):5817-5832. doi: 10.1172/JCI98882. J Clin Invest. 2020. PMID: 32750042 Free PMC article.
Dendritic cell therapy with CD137L-DC-EBV-VAX in locally recurrent or metastatic nasopharyngeal carcinoma is safe and confers clinical benefit.
Nickles E, Dharmadhikari B, Yating L, Walsh RJ, Koh LP, Poon M, Tan LK, Wang LZ, Ang Y, Asokumaran Y, Chong WQ, Huang Y, Loh KS, Tay J, Soo R, Koh M, Ho LP, Chan M, Niam M, Soh M, Luah YH, Lim CM, Kaliaperumal N, Au VB, Talib NBSN, Sng R, Connolly JE, Goh BC, Schwarz H. Nickles E, et al. Among authors: kaliaperumal n. Cancer Immunol Immunother. 2022 Jun;71(6):1531-1543. doi: 10.1007/s00262-021-03075-3. Epub 2021 Oct 18. Cancer Immunol Immunother. 2022. PMID: 34661709 Free PMC article. Clinical Trial.
First-in-Human Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Rapidly Developed SARS-CoV-2 Therapeutic Antibody, AOD01, in Healthy Adults.
Prativadibhayankaram VS, Lee LS, Lye D, Xiaoying X, Nellore R, Pendharkar V, Hentze H, Guan S, Ayers BJ, Seah SGK, Chye H, Talib NSN, Kaliaperumal N, Ong WY, Wong ZX, Au VB, Alok A, Connolly JE, Boyd-Kirkup JD, Ingram PJ, Hanson BJ, Ethirajulu K, O'Connell D, Chan CEZ. Prativadibhayankaram VS, et al. Among authors: kaliaperumal n. Infect Dis Ther. 2022 Oct;11(5):1999-2015. doi: 10.1007/s40121-022-00681-1. Epub 2022 Sep 4. Infect Dis Ther. 2022. PMID: 36058990 Free PMC article.
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